Molecular Responses to the Zika Virus in Mosquitoes
The Zika virus (ZIKV), originally discovered in 1947, did not become a major concern until the virus swept across the Pacific and into the Americas in the last decade, bringing with it news of neurological complications and birth defects in ZIKV affected areas. This prompted researchers to dissect t...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-05-01
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| Series: | Pathogens |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2076-0817/7/2/49 |
| _version_ | 1798004009043230720 |
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| author | Catalina Alfonso-Parra Frank W. Avila |
| author_facet | Catalina Alfonso-Parra Frank W. Avila |
| author_sort | Catalina Alfonso-Parra |
| collection | DOAJ |
| description | The Zika virus (ZIKV), originally discovered in 1947, did not become a major concern until the virus swept across the Pacific and into the Americas in the last decade, bringing with it news of neurological complications and birth defects in ZIKV affected areas. This prompted researchers to dissect the molecular interactions between ZIKV and the mosquito vector in an attempt to better understand not only the changes that occur upon infection, but to also identify molecules that may potentially enhance or suppress a mosquito’s ability to become infected and/or transmit the virus. Here, we review what is currently known regarding ZIKV-mosquito molecular interactions, focusing on ZIKV infection of Aedes aegypti and Aedes albopictus, the primary species implicated in transmitting ZIKV during the recent outbreaks. |
| first_indexed | 2024-04-11T12:16:44Z |
| format | Article |
| id | doaj.art-02d49c9b2906437480b1fa770728d4b3 |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-04-11T12:16:44Z |
| publishDate | 2018-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-02d49c9b2906437480b1fa770728d4b32022-12-22T04:24:15ZengMDPI AGPathogens2076-08172018-05-01724910.3390/pathogens7020049pathogens7020049Molecular Responses to the Zika Virus in MosquitoesCatalina Alfonso-Parra0Frank W. Avila1Max Planck Tandem Group in Mosquito Reproductive Biology, University of Antioquia, Calle 67 #53-108, Medellín 050010, ColombiaMax Planck Tandem Group in Mosquito Reproductive Biology, University of Antioquia, Calle 67 #53-108, Medellín 050010, ColombiaThe Zika virus (ZIKV), originally discovered in 1947, did not become a major concern until the virus swept across the Pacific and into the Americas in the last decade, bringing with it news of neurological complications and birth defects in ZIKV affected areas. This prompted researchers to dissect the molecular interactions between ZIKV and the mosquito vector in an attempt to better understand not only the changes that occur upon infection, but to also identify molecules that may potentially enhance or suppress a mosquito’s ability to become infected and/or transmit the virus. Here, we review what is currently known regarding ZIKV-mosquito molecular interactions, focusing on ZIKV infection of Aedes aegypti and Aedes albopictus, the primary species implicated in transmitting ZIKV during the recent outbreaks.http://www.mdpi.com/2076-0817/7/2/49FlavivirusZIKVAedes aegyptiAedes albopictus |
| spellingShingle | Catalina Alfonso-Parra Frank W. Avila Molecular Responses to the Zika Virus in Mosquitoes Pathogens Flavivirus ZIKV Aedes aegypti Aedes albopictus |
| title | Molecular Responses to the Zika Virus in Mosquitoes |
| title_full | Molecular Responses to the Zika Virus in Mosquitoes |
| title_fullStr | Molecular Responses to the Zika Virus in Mosquitoes |
| title_full_unstemmed | Molecular Responses to the Zika Virus in Mosquitoes |
| title_short | Molecular Responses to the Zika Virus in Mosquitoes |
| title_sort | molecular responses to the zika virus in mosquitoes |
| topic | Flavivirus ZIKV Aedes aegypti Aedes albopictus |
| url | http://www.mdpi.com/2076-0817/7/2/49 |
| work_keys_str_mv | AT catalinaalfonsoparra molecularresponsestothezikavirusinmosquitoes AT frankwavila molecularresponsestothezikavirusinmosquitoes |