Statines in pregnancy

Until a few years ago, the classification of the Food and Drug Administration (FDA) to indicate the level of risk of drugs on the fetus established five categories (A, B, C, D, X). Category X included contraindicated drugs, among which were statins. That is to say, there was a formal contraindicatio...

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Bibliographic Details
Main Author: Susana Salzberg
Format: Article
Language:Spanish
Published: Sello Editorial Lugones 2022-09-01
Series:Revista de la Sociedad Argentina de Diabetes
Subjects:
Online Access:https://revistasad.com/index.php/diabetes/article/view/607
Description
Summary:Until a few years ago, the classification of the Food and Drug Administration (FDA) to indicate the level of risk of drugs on the fetus established five categories (A, B, C, D, X). Category X included contraindicated drugs, among which were statins. That is to say, there was a formal contraindication for statins to be used during pregnancy, or in women who could become pregnant, due to their possible teratogenic effects. Studies published after this categorization provided new data on the subject. In particular, they question the positive association between the use of statins in the embryogenic period and congenital malformations. Some studies have even shown that intrauterine exposure to statins favors prematurity and/or low birth weight.
ISSN:0325-5247
2346-9420