The Clinical Course and Outcomes of Patients Hospitalized Due to COVID-19 during Three Pandemic Waves in Poland: A Single Center Observational Study
Background: The first case of coronavirus disease 2019 (COVID-19) in Poland was reported on 4 March 2020. We aim to compare the clinical course and outcomes of patients hospitalized in the Hospital for Infectious Diseases in Warsaw due to COVID-19 during three pandemic waves. Materials and methods:...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/24/7386 |
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| author | Carlo Bieńkowski Justyna D. Kowalska Marcin Paciorek Piotr Wasilewski Paweł Uliczny Ewelina Garbacz-Łagożna Andrzej Pihowicz Monika Mrozińska Tomasz Dyda Michał Makowiecki Joanna Puła Andrzej Horban |
| author_facet | Carlo Bieńkowski Justyna D. Kowalska Marcin Paciorek Piotr Wasilewski Paweł Uliczny Ewelina Garbacz-Łagożna Andrzej Pihowicz Monika Mrozińska Tomasz Dyda Michał Makowiecki Joanna Puła Andrzej Horban |
| author_sort | Carlo Bieńkowski |
| collection | DOAJ |
| description | Background: The first case of coronavirus disease 2019 (COVID-19) in Poland was reported on 4 March 2020. We aim to compare the clinical course and outcomes of patients hospitalized in the Hospital for Infectious Diseases in Warsaw due to COVID-19 during three pandemic waves. Materials and methods: The medical data were collected for all patients diagnosed with COVID-19 hospitalized in our hospital from 6 March 2020 till 30 November 2021. COVID-19 diagnosis was confirmed by nasopharyngeal swabs using real-time polymerase chain reaction assay (RT-PCR) or SARS-CoV-2 antigen test. COVID-19 waves were defined based on the number and dynamics of cases. Results: Altogether, 2138 patient medical records were analyzed. The majority of the cohort was male (1235/2138, 57.8%), and the median age was 65 years [IQR: 50–74 years]. Patients hospitalized during the third wave had lower oxygen saturation on admission (<i>p</i> < 0.001) and were more likely to receive oxygen supplementation (<i>p</i> < 0.001). Serious complications, including pneumothorax (<i>p</i> < 0.001) and thromboembolic complications (<i>p</i> < 0.001), intensive care unit admission (<i>p</i> = 0.034), and death (<i>p</i> = 0.003), occurred more often in patients of the third wave. Conclusions: During the third wave, patients in our cohort experienced a more severe course of the disease and poorer outcomes. |
| first_indexed | 2024-03-09T16:16:25Z |
| format | Article |
| id | doaj.art-02d4ff7d6a624eac8cba42f99835abac |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T16:16:25Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-02d4ff7d6a624eac8cba42f99835abac2023-11-24T15:44:43ZengMDPI AGJournal of Clinical Medicine2077-03832022-12-011124738610.3390/jcm11247386The Clinical Course and Outcomes of Patients Hospitalized Due to COVID-19 during Three Pandemic Waves in Poland: A Single Center Observational StudyCarlo Bieńkowski0Justyna D. Kowalska1Marcin Paciorek2Piotr Wasilewski3Paweł Uliczny4Ewelina Garbacz-Łagożna5Andrzej Pihowicz6Monika Mrozińska7Tomasz Dyda8Michał Makowiecki9Joanna Puła10Andrzej Horban11Hospital for Infectious Diseases in Warsaw, 01-201 Warsaw, PolandHospital for Infectious Diseases in Warsaw, 01-201 Warsaw, PolandHospital for Infectious Diseases in Warsaw, 01-201 Warsaw, PolandHospital for Infectious Diseases in Warsaw, 01-201 Warsaw, PolandHospital for Infectious Diseases in Warsaw, 01-201 Warsaw, PolandHospital for Infectious Diseases in Warsaw, 01-201 Warsaw, PolandHospital for Infectious Diseases in Warsaw, 01-201 Warsaw, PolandHospital for Infectious Diseases in Warsaw, 01-201 Warsaw, PolandHospital for Infectious Diseases in Warsaw, 01-201 Warsaw, PolandHospital for Infectious Diseases in Warsaw, 01-201 Warsaw, PolandHospital for Infectious Diseases in Warsaw, 01-201 Warsaw, PolandHospital for Infectious Diseases in Warsaw, 01-201 Warsaw, PolandBackground: The first case of coronavirus disease 2019 (COVID-19) in Poland was reported on 4 March 2020. We aim to compare the clinical course and outcomes of patients hospitalized in the Hospital for Infectious Diseases in Warsaw due to COVID-19 during three pandemic waves. Materials and methods: The medical data were collected for all patients diagnosed with COVID-19 hospitalized in our hospital from 6 March 2020 till 30 November 2021. COVID-19 diagnosis was confirmed by nasopharyngeal swabs using real-time polymerase chain reaction assay (RT-PCR) or SARS-CoV-2 antigen test. COVID-19 waves were defined based on the number and dynamics of cases. Results: Altogether, 2138 patient medical records were analyzed. The majority of the cohort was male (1235/2138, 57.8%), and the median age was 65 years [IQR: 50–74 years]. Patients hospitalized during the third wave had lower oxygen saturation on admission (<i>p</i> < 0.001) and were more likely to receive oxygen supplementation (<i>p</i> < 0.001). Serious complications, including pneumothorax (<i>p</i> < 0.001) and thromboembolic complications (<i>p</i> < 0.001), intensive care unit admission (<i>p</i> = 0.034), and death (<i>p</i> = 0.003), occurred more often in patients of the third wave. Conclusions: During the third wave, patients in our cohort experienced a more severe course of the disease and poorer outcomes.https://www.mdpi.com/2077-0383/11/24/7386COVID-19SARS-CoV-2pandemicepidemic waves |
| spellingShingle | Carlo Bieńkowski Justyna D. Kowalska Marcin Paciorek Piotr Wasilewski Paweł Uliczny Ewelina Garbacz-Łagożna Andrzej Pihowicz Monika Mrozińska Tomasz Dyda Michał Makowiecki Joanna Puła Andrzej Horban The Clinical Course and Outcomes of Patients Hospitalized Due to COVID-19 during Three Pandemic Waves in Poland: A Single Center Observational Study Journal of Clinical Medicine COVID-19 SARS-CoV-2 pandemic epidemic waves |
| title | The Clinical Course and Outcomes of Patients Hospitalized Due to COVID-19 during Three Pandemic Waves in Poland: A Single Center Observational Study |
| title_full | The Clinical Course and Outcomes of Patients Hospitalized Due to COVID-19 during Three Pandemic Waves in Poland: A Single Center Observational Study |
| title_fullStr | The Clinical Course and Outcomes of Patients Hospitalized Due to COVID-19 during Three Pandemic Waves in Poland: A Single Center Observational Study |
| title_full_unstemmed | The Clinical Course and Outcomes of Patients Hospitalized Due to COVID-19 during Three Pandemic Waves in Poland: A Single Center Observational Study |
| title_short | The Clinical Course and Outcomes of Patients Hospitalized Due to COVID-19 during Three Pandemic Waves in Poland: A Single Center Observational Study |
| title_sort | clinical course and outcomes of patients hospitalized due to covid 19 during three pandemic waves in poland a single center observational study |
| topic | COVID-19 SARS-CoV-2 pandemic epidemic waves |
| url | https://www.mdpi.com/2077-0383/11/24/7386 |
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