Emergence of Plasmodium falciparum strains with artemisinin partial resistance in East Africa and the Horn of Africa: is there a need to panic?
Abstract The emergence and spread of artemisinin partial resistance in East and Horn of Africa is alarming. However, artemisinin-based combination therapy (ACT) generally remains efficacious for the treatment of falciparum malaria. The emergence of partial artemisinin resistance does not currently m...
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| Format: | Article |
| Language: | English |
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BMC
2024-01-01
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| Series: | Malaria Journal |
| Online Access: | https://doi.org/10.1186/s12936-024-04848-8 |
| _version_ | 1797340260209786880 |
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| author | Ashenafi Assefa Abebe A. Fola Geremew Tasew |
| author_facet | Ashenafi Assefa Abebe A. Fola Geremew Tasew |
| author_sort | Ashenafi Assefa |
| collection | DOAJ |
| description | Abstract The emergence and spread of artemisinin partial resistance in East and Horn of Africa is alarming. However, artemisinin-based combination therapy (ACT) generally remains efficacious for the treatment of falciparum malaria. The emergence of partial artemisinin resistance does not currently meet the criteria to initiate change on treatment guidelines nor affect ACT routine procurement and distribution. It is high time for scientists and transitional researchers to be more critical and vigilant on further changes so that national programmes will be able to make informed decisions as well as remain alert and prepared for any change that may be required in the future. |
| first_indexed | 2024-03-08T10:00:26Z |
| format | Article |
| id | doaj.art-02d9075a9d094c309599312d37a6b479 |
| institution | Directory Open Access Journal |
| issn | 1475-2875 |
| language | English |
| last_indexed | 2024-03-08T10:00:26Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Malaria Journal |
| spelling | doaj.art-02d9075a9d094c309599312d37a6b4792024-01-29T10:59:21ZengBMCMalaria Journal1475-28752024-01-012311410.1186/s12936-024-04848-8Emergence of Plasmodium falciparum strains with artemisinin partial resistance in East Africa and the Horn of Africa: is there a need to panic?Ashenafi Assefa0Abebe A. Fola1Geremew Tasew2Ethiopian Public Health InstituteCenter for Computational Molecular Biology, Brown UniversityEthiopian Public Health InstituteAbstract The emergence and spread of artemisinin partial resistance in East and Horn of Africa is alarming. However, artemisinin-based combination therapy (ACT) generally remains efficacious for the treatment of falciparum malaria. The emergence of partial artemisinin resistance does not currently meet the criteria to initiate change on treatment guidelines nor affect ACT routine procurement and distribution. It is high time for scientists and transitional researchers to be more critical and vigilant on further changes so that national programmes will be able to make informed decisions as well as remain alert and prepared for any change that may be required in the future.https://doi.org/10.1186/s12936-024-04848-8 |
| spellingShingle | Ashenafi Assefa Abebe A. Fola Geremew Tasew Emergence of Plasmodium falciparum strains with artemisinin partial resistance in East Africa and the Horn of Africa: is there a need to panic? Malaria Journal |
| title | Emergence of Plasmodium falciparum strains with artemisinin partial resistance in East Africa and the Horn of Africa: is there a need to panic? |
| title_full | Emergence of Plasmodium falciparum strains with artemisinin partial resistance in East Africa and the Horn of Africa: is there a need to panic? |
| title_fullStr | Emergence of Plasmodium falciparum strains with artemisinin partial resistance in East Africa and the Horn of Africa: is there a need to panic? |
| title_full_unstemmed | Emergence of Plasmodium falciparum strains with artemisinin partial resistance in East Africa and the Horn of Africa: is there a need to panic? |
| title_short | Emergence of Plasmodium falciparum strains with artemisinin partial resistance in East Africa and the Horn of Africa: is there a need to panic? |
| title_sort | emergence of plasmodium falciparum strains with artemisinin partial resistance in east africa and the horn of africa is there a need to panic |
| url | https://doi.org/10.1186/s12936-024-04848-8 |
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