To sleep or not to sleep: An Italian Control-IQ-uestion

ObjectiveTandem Control-IQ is an advanced hybrid closed loop (AHCL) system with a Sleep Activity Mode to intensify glycemic control overnight. The aim of the study is to evaluate the effectiveness of using Sleep Mode or not among Tandem Control-IQ users.Research design and methodsWe performed a retr...

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Main Authors: Marta Bassi, Marina Francesca Strati, Valentina Andreottola, Maria Grazia Calevo, Giuseppe d’Annunzio, Mohamad Maghnie, Nicola Minuto
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.996453/full
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author Marta Bassi
Marta Bassi
Marina Francesca Strati
Marina Francesca Strati
Valentina Andreottola
Valentina Andreottola
Maria Grazia Calevo
Giuseppe d’Annunzio
Mohamad Maghnie
Mohamad Maghnie
Nicola Minuto
author_facet Marta Bassi
Marta Bassi
Marina Francesca Strati
Marina Francesca Strati
Valentina Andreottola
Valentina Andreottola
Maria Grazia Calevo
Giuseppe d’Annunzio
Mohamad Maghnie
Mohamad Maghnie
Nicola Minuto
author_sort Marta Bassi
collection DOAJ
description ObjectiveTandem Control-IQ is an advanced hybrid closed loop (AHCL) system with a Sleep Activity Mode to intensify glycemic control overnight. The aim of the study is to evaluate the effectiveness of using Sleep Mode or not among Tandem Control-IQ users.Research design and methodsWe performed a retrospective Tandem Control-IQ data download for patients followed at IRCCS G. Gaslini Pediatric Diabetes Centre. We divided the patients into group 1 (Sleep Mode users) and group 2 (non-users) and compared their overall glycemic data, particularly during nighttime.ResultsGroup 1 (n = 49) does not show better nocturnal glycemic control as expected when compared with group 2 (n = 34). Group 2 shows a nighttime TIR% of 69.50 versus 66.25 (p = 0.20). Only the patients who do not use Sleep Mode and with sensor and automatic mode use ≥90% reached TIR >70% during nighttime, as well as lower nocturnal TAR% (18.80 versus 21.78, p = 0.05).ConclusionsThis is the first study that evaluates the real-life effectiveness of the use of Sleep Mode in young patients with T1D. Control-IQ Sleep Activity Mode may not be as effective in Italian patients as in American patients due to the different habits.
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spelling doaj.art-02dd5518f4f6438abf17a4e7af0f8d2e2022-12-22T04:41:23ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922022-12-011310.3389/fendo.2022.996453996453To sleep or not to sleep: An Italian Control-IQ-uestionMarta Bassi0Marta Bassi1Marina Francesca Strati2Marina Francesca Strati3Valentina Andreottola4Valentina Andreottola5Maria Grazia Calevo6Giuseppe d’Annunzio7Mohamad Maghnie8Mohamad Maghnie9Nicola Minuto10Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, ItalyDepartment of Pediatrics, IRCCS Istituto Giannina Gaslini, Genoa, ItalyDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, ItalyDepartment of Pediatrics, IRCCS Istituto Giannina Gaslini, Genoa, ItalyDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, ItalyDepartment of Pediatrics, IRCCS Istituto Giannina Gaslini, Genoa, ItalyEpidemiology and Biostatistics Unit, IRCCS Istituto Giannina Gaslini, Genoa, ItalyDepartment of Pediatrics, IRCCS Istituto Giannina Gaslini, Genoa, ItalyDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, ItalyDepartment of Pediatrics, IRCCS Istituto Giannina Gaslini, Genoa, ItalyDepartment of Pediatrics, IRCCS Istituto Giannina Gaslini, Genoa, ItalyObjectiveTandem Control-IQ is an advanced hybrid closed loop (AHCL) system with a Sleep Activity Mode to intensify glycemic control overnight. The aim of the study is to evaluate the effectiveness of using Sleep Mode or not among Tandem Control-IQ users.Research design and methodsWe performed a retrospective Tandem Control-IQ data download for patients followed at IRCCS G. Gaslini Pediatric Diabetes Centre. We divided the patients into group 1 (Sleep Mode users) and group 2 (non-users) and compared their overall glycemic data, particularly during nighttime.ResultsGroup 1 (n = 49) does not show better nocturnal glycemic control as expected when compared with group 2 (n = 34). Group 2 shows a nighttime TIR% of 69.50 versus 66.25 (p = 0.20). Only the patients who do not use Sleep Mode and with sensor and automatic mode use ≥90% reached TIR >70% during nighttime, as well as lower nocturnal TAR% (18.80 versus 21.78, p = 0.05).ConclusionsThis is the first study that evaluates the real-life effectiveness of the use of Sleep Mode in young patients with T1D. Control-IQ Sleep Activity Mode may not be as effective in Italian patients as in American patients due to the different habits.https://www.frontiersin.org/articles/10.3389/fendo.2022.996453/fullTIR (time in range)CGM (continuous glucose monitoring)Type 1 diabetes (T1D)tandem control-IQsleepAHCL (Advanced Hybrid Closed Loop)
spellingShingle Marta Bassi
Marta Bassi
Marina Francesca Strati
Marina Francesca Strati
Valentina Andreottola
Valentina Andreottola
Maria Grazia Calevo
Giuseppe d’Annunzio
Mohamad Maghnie
Mohamad Maghnie
Nicola Minuto
To sleep or not to sleep: An Italian Control-IQ-uestion
Frontiers in Endocrinology
TIR (time in range)
CGM (continuous glucose monitoring)
Type 1 diabetes (T1D)
tandem control-IQ
sleep
AHCL (Advanced Hybrid Closed Loop)
title To sleep or not to sleep: An Italian Control-IQ-uestion
title_full To sleep or not to sleep: An Italian Control-IQ-uestion
title_fullStr To sleep or not to sleep: An Italian Control-IQ-uestion
title_full_unstemmed To sleep or not to sleep: An Italian Control-IQ-uestion
title_short To sleep or not to sleep: An Italian Control-IQ-uestion
title_sort to sleep or not to sleep an italian control iq uestion
topic TIR (time in range)
CGM (continuous glucose monitoring)
Type 1 diabetes (T1D)
tandem control-IQ
sleep
AHCL (Advanced Hybrid Closed Loop)
url https://www.frontiersin.org/articles/10.3389/fendo.2022.996453/full
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