Fn14 and TNFR2 as regulators of cytotoxic TNFR1 signaling

Fn14 and TNFR2 as regulators of cytotoxic TNFR1 signaling

Tumor necrosis factor (TNF) receptor 1 (TNFR1), TNFR2 and fibroblast growth factor-inducible 14 (Fn14) belong to the TNF receptor superfamily (TNFRSF). From a structural point of view, TNFR1 is a prototypic death domain (DD)-containing receptor. In contrast to other prominent death receptors, such a...

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Bibliographic Details
Main Authors: Daniela Siegmund, Olena Zaitseva, Harald Wajant
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
apoptosis
Fn14
necroptosis
TNF
TNFR1
TNFR2
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1267837/full

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