Public Databases and Software for the Pathway Analysis of Cancer Genomes
The study of pathway disruption is key to understanding cancer biology. Advances in high throughput technologies have led to the rapid accumulation of genomic data. The explosion in available data has generated opportunities for investigation of concerted changes that disrupt biological functions, t...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
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SAGE Publishing
2007-01-01
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Series: | Cancer Informatics |
Online Access: | https://doi.org/10.1177/117693510700300027 |
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author | Ivy F.L. Tsui Raj Chari Timon P.H. Buys Wan L. Lam |
author_facet | Ivy F.L. Tsui Raj Chari Timon P.H. Buys Wan L. Lam |
author_sort | Ivy F.L. Tsui |
collection | DOAJ |
description | The study of pathway disruption is key to understanding cancer biology. Advances in high throughput technologies have led to the rapid accumulation of genomic data. The explosion in available data has generated opportunities for investigation of concerted changes that disrupt biological functions, this in turns created a need for computational tools for pathway analysis. In this review, we discuss approaches to the analysis of genomic data and describe the publicly available resources for studying biological pathways. |
first_indexed | 2024-04-12T01:39:04Z |
format | Article |
id | doaj.art-02e2d2c9db974b03959e23bf76791576 |
institution | Directory Open Access Journal |
issn | 1176-9351 |
language | English |
last_indexed | 2024-04-12T01:39:04Z |
publishDate | 2007-01-01 |
publisher | SAGE Publishing |
record_format | Article |
series | Cancer Informatics |
spelling | doaj.art-02e2d2c9db974b03959e23bf767915762022-12-22T03:53:14ZengSAGE PublishingCancer Informatics1176-93512007-01-01310.1177/117693510700300027Public Databases and Software for the Pathway Analysis of Cancer GenomesIvy F.L. Tsui0Raj Chari1Timon P.H. Buys2Wan L. Lam3Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.The study of pathway disruption is key to understanding cancer biology. Advances in high throughput technologies have led to the rapid accumulation of genomic data. The explosion in available data has generated opportunities for investigation of concerted changes that disrupt biological functions, this in turns created a need for computational tools for pathway analysis. In this review, we discuss approaches to the analysis of genomic data and describe the publicly available resources for studying biological pathways.https://doi.org/10.1177/117693510700300027 |
spellingShingle | Ivy F.L. Tsui Raj Chari Timon P.H. Buys Wan L. Lam Public Databases and Software for the Pathway Analysis of Cancer Genomes Cancer Informatics |
title | Public Databases and Software for the Pathway Analysis of Cancer Genomes |
title_full | Public Databases and Software for the Pathway Analysis of Cancer Genomes |
title_fullStr | Public Databases and Software for the Pathway Analysis of Cancer Genomes |
title_full_unstemmed | Public Databases and Software for the Pathway Analysis of Cancer Genomes |
title_short | Public Databases and Software for the Pathway Analysis of Cancer Genomes |
title_sort | public databases and software for the pathway analysis of cancer genomes |
url | https://doi.org/10.1177/117693510700300027 |
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