Public Databases and Software for the Pathway Analysis of Cancer Genomes

The study of pathway disruption is key to understanding cancer biology. Advances in high throughput technologies have led to the rapid accumulation of genomic data. The explosion in available data has generated opportunities for investigation of concerted changes that disrupt biological functions, t...

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Main Authors: Ivy F.L. Tsui, Raj Chari, Timon P.H. Buys, Wan L. Lam
Format: Article
Language:English
Published: SAGE Publishing 2007-01-01
Series:Cancer Informatics
Online Access:https://doi.org/10.1177/117693510700300027
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author Ivy F.L. Tsui
Raj Chari
Timon P.H. Buys
Wan L. Lam
author_facet Ivy F.L. Tsui
Raj Chari
Timon P.H. Buys
Wan L. Lam
author_sort Ivy F.L. Tsui
collection DOAJ
description The study of pathway disruption is key to understanding cancer biology. Advances in high throughput technologies have led to the rapid accumulation of genomic data. The explosion in available data has generated opportunities for investigation of concerted changes that disrupt biological functions, this in turns created a need for computational tools for pathway analysis. In this review, we discuss approaches to the analysis of genomic data and describe the publicly available resources for studying biological pathways.
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spelling doaj.art-02e2d2c9db974b03959e23bf767915762022-12-22T03:53:14ZengSAGE PublishingCancer Informatics1176-93512007-01-01310.1177/117693510700300027Public Databases and Software for the Pathway Analysis of Cancer GenomesIvy F.L. Tsui0Raj Chari1Timon P.H. Buys2Wan L. Lam3Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.The study of pathway disruption is key to understanding cancer biology. Advances in high throughput technologies have led to the rapid accumulation of genomic data. The explosion in available data has generated opportunities for investigation of concerted changes that disrupt biological functions, this in turns created a need for computational tools for pathway analysis. In this review, we discuss approaches to the analysis of genomic data and describe the publicly available resources for studying biological pathways.https://doi.org/10.1177/117693510700300027
spellingShingle Ivy F.L. Tsui
Raj Chari
Timon P.H. Buys
Wan L. Lam
Public Databases and Software for the Pathway Analysis of Cancer Genomes
Cancer Informatics
title Public Databases and Software for the Pathway Analysis of Cancer Genomes
title_full Public Databases and Software for the Pathway Analysis of Cancer Genomes
title_fullStr Public Databases and Software for the Pathway Analysis of Cancer Genomes
title_full_unstemmed Public Databases and Software for the Pathway Analysis of Cancer Genomes
title_short Public Databases and Software for the Pathway Analysis of Cancer Genomes
title_sort public databases and software for the pathway analysis of cancer genomes
url https://doi.org/10.1177/117693510700300027
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