Viscoelastic coagulation test for liver transplantation

Coagulation and transfusion management in patients undergoing liver transplantation is challenging. Proper perioperative monitoring of hemostasis is essential to predict the risk of bleeding during surgery, to detect potential causes of hemorrhage in time, and to guide hemostatic therapy. The value...

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Main Author: Sun Young Park
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2020-04-01
Series:Anesthesia and Pain Medicine
Subjects:
Online Access:http://www.anesth-pain-med.org/upload/pdf/apm-2020-15-2-143.pdf
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author Sun Young Park
author_facet Sun Young Park
author_sort Sun Young Park
collection DOAJ
description Coagulation and transfusion management in patients undergoing liver transplantation is challenging. Proper perioperative monitoring of hemostasis is essential to predict the risk of bleeding during surgery, to detect potential causes of hemorrhage in time, and to guide hemostatic therapy. The value of conventional coagulation test is questionable in the acute perioperative setting due to their long turnaround time and the inability to adequately reflect the complex changes in hemostasis in patients with liver disease. Viscoelastic coagulation tests provide simultaneous measurement of multiple aspects of whole-blood coagulation including plasmatic coagulation and fibrinolytic factors and inhibitors that reflect most aspects of hemostasis. Coagulation initiation, mechanical clot stability, and fibrinolysis can be estimated immediately using point-of-care techniques. Therefore, viscoelastic coagulation tests including ROTEM & TEG would be useful to guide patient blood management strategy during liver transplantation.
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spelling doaj.art-02e7f6f411ec4525b15fe8d48a4d3f312023-05-17T05:33:43ZengKorean Society of AnesthesiologistsAnesthesia and Pain Medicine1975-51712383-79772020-04-0115214315110.17085/apm.2020.15.2.1431013Viscoelastic coagulation test for liver transplantationSun Young Park0 Department of Anesthesiology and Pain Medicine, Soonchunhyang University Seoul Hospital, Seoul, KoreaCoagulation and transfusion management in patients undergoing liver transplantation is challenging. Proper perioperative monitoring of hemostasis is essential to predict the risk of bleeding during surgery, to detect potential causes of hemorrhage in time, and to guide hemostatic therapy. The value of conventional coagulation test is questionable in the acute perioperative setting due to their long turnaround time and the inability to adequately reflect the complex changes in hemostasis in patients with liver disease. Viscoelastic coagulation tests provide simultaneous measurement of multiple aspects of whole-blood coagulation including plasmatic coagulation and fibrinolytic factors and inhibitors that reflect most aspects of hemostasis. Coagulation initiation, mechanical clot stability, and fibrinolysis can be estimated immediately using point-of-care techniques. Therefore, viscoelastic coagulation tests including ROTEM & TEG would be useful to guide patient blood management strategy during liver transplantation.http://www.anesth-pain-med.org/upload/pdf/apm-2020-15-2-143.pdfblood coagulation disordersblood coagulation testsliver transplantationthromboelastography
spellingShingle Sun Young Park
Viscoelastic coagulation test for liver transplantation
Anesthesia and Pain Medicine
blood coagulation disorders
blood coagulation tests
liver transplantation
thromboelastography
title Viscoelastic coagulation test for liver transplantation
title_full Viscoelastic coagulation test for liver transplantation
title_fullStr Viscoelastic coagulation test for liver transplantation
title_full_unstemmed Viscoelastic coagulation test for liver transplantation
title_short Viscoelastic coagulation test for liver transplantation
title_sort viscoelastic coagulation test for liver transplantation
topic blood coagulation disorders
blood coagulation tests
liver transplantation
thromboelastography
url http://www.anesth-pain-med.org/upload/pdf/apm-2020-15-2-143.pdf
work_keys_str_mv AT sunyoungpark viscoelasticcoagulationtestforlivertransplantation