Chemotherapy Shifts the Balance in Favor of CD8+ TNFR2+ TILs in Triple-Negative Breast Tumors

Chemotherapy Shifts the Balance in Favor of CD8+ TNFR2+ TILs in Triple-Negative Breast Tumors

Triple-negative breast cancer (TNBC) is primarily treated via chemotherapy; in parallel, efforts are made to introduce immunotherapies into TNBC treatment. CD4+ TNFR2+ lymphocytes were reported as Tregs that contribute to tumor progression. However, our published study indicated that TNFR2+ tumor-in...

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Bibliographic Details
Main Authors:	Tamir Baram, Nofar Erlichman, Maya Dadiani, Nora Balint-Lahat, Anya Pavlovski, Tsipi Meshel, Dana Morzaev-Sulzbach, Einav Nili Gal-Yam, Iris Barshack, Adit Ben-Baruch
Format:	Article
Language:	English
Published:	MDPI AG 2021-06-01
Series:	Cells
Subjects:	CD4+ lymphocytes CD8+ lymphocytes forkhead box P3 (FOXP3) programmed cell death protein 1 (PD-1) splenocytes triple-negative breast cancer (TNBC)
Online Access:	https://www.mdpi.com/2073-4409/10/6/1429

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