Novel Developments in Hypomimia in Parkinson's Disease

Hypomimia is one prominent clinical symptom of Parkinson's disease (PD) , which is mainly characterized by a loss or reduction of voluntary, emotional and other facial expressions, and usually appears bilaterally and symmetrically. Factors associated with hypomimia in PD have been extensive...

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Main Author: Gen HUANG, Huimin CAO, Gang YU
Format: Article
Language:zho
Published: Chinese General Practice Publishing House Co., Ltd 2022-07-01
Series:Zhongguo quanke yixue
Subjects:
Online Access:https://www.chinagp.net/fileup/1007-9572/PDF/zx20220245.pdf
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author Gen HUANG, Huimin CAO, Gang YU
author_facet Gen HUANG, Huimin CAO, Gang YU
author_sort Gen HUANG, Huimin CAO, Gang YU
collection DOAJ
description Hypomimia is one prominent clinical symptom of Parkinson's disease (PD) , which is mainly characterized by a loss or reduction of voluntary, emotional and other facial expressions, and usually appears bilaterally and symmetrically. Factors associated with hypomimia in PD have been extensively studied recently, including basal ganglia dysfunction, facial emotion recognition deficit, and cognitive impairment, but the specific pathophysiological mechanism is still unclear. Hypomimia strongly correlates with the progression of PD, so scientific quantification and evaluation of hypomimia will be of great significance to the diagnosis and treatment of PD. Besides that, there is still controversy over its treatment plan. We reviewed the latest developments in clinical presentations, pathogenesis and treatment of hypomimia in PD.
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spelling doaj.art-02ecabfba4e040fb98d62f74a55958d82024-04-09T03:37:48ZzhoChinese General Practice Publishing House Co., LtdZhongguo quanke yixue1007-95722022-07-0125202558256210.12114/j.issn.1007-9572.2022.0245Novel Developments in Hypomimia in Parkinson's DiseaseGen HUANG, Huimin CAO, Gang YU0Department of Neurology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, ChinaHypomimia is one prominent clinical symptom of Parkinson's disease (PD) , which is mainly characterized by a loss or reduction of voluntary, emotional and other facial expressions, and usually appears bilaterally and symmetrically. Factors associated with hypomimia in PD have been extensively studied recently, including basal ganglia dysfunction, facial emotion recognition deficit, and cognitive impairment, but the specific pathophysiological mechanism is still unclear. Hypomimia strongly correlates with the progression of PD, so scientific quantification and evaluation of hypomimia will be of great significance to the diagnosis and treatment of PD. Besides that, there is still controversy over its treatment plan. We reviewed the latest developments in clinical presentations, pathogenesis and treatment of hypomimia in PD.https://www.chinagp.net/fileup/1007-9572/PDF/zx20220245.pdfparkinson disease|facial expression|hypomimia|signs and symptoms mechanism|therapy
spellingShingle Gen HUANG, Huimin CAO, Gang YU
Novel Developments in Hypomimia in Parkinson's Disease
Zhongguo quanke yixue
parkinson disease|facial expression|hypomimia|signs and symptoms mechanism|therapy
title Novel Developments in Hypomimia in Parkinson's Disease
title_full Novel Developments in Hypomimia in Parkinson's Disease
title_fullStr Novel Developments in Hypomimia in Parkinson's Disease
title_full_unstemmed Novel Developments in Hypomimia in Parkinson's Disease
title_short Novel Developments in Hypomimia in Parkinson's Disease
title_sort novel developments in hypomimia in parkinson apos s disease
topic parkinson disease|facial expression|hypomimia|signs and symptoms mechanism|therapy
url https://www.chinagp.net/fileup/1007-9572/PDF/zx20220245.pdf
work_keys_str_mv AT genhuanghuimincaogangyu noveldevelopmentsinhypomimiainparkinsonapossdisease