Combined HIV Adolescent Prevention Study (CHAPS): comparison of HIV pre-exposure prophylaxis regimens for adolescents in sub-Saharan Africa—study protocol for a mixed-methods study including a randomised controlled trial

Combined HIV Adolescent Prevention Study (CHAPS): comparison of HIV pre-exposure prophylaxis regimens for adolescents in sub-Saharan Africa—study protocol for a mixed-methods study including a randomised controlled trial

Abstract Background HIV remains a major public health issue, especially in Eastern and Southern Africa. Pre-exposure prophylaxis is highly effective when adhered to, but its effectiveness is limited by cost, user acceptability and uptake. The cost of a non-inferiority phase III trial is likely to be...

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Bibliographic Details
Main Authors: S. Nash, J. Dietrich, A. S. Ssemata, C. Herrera, K. O’Hagan, L. Else, F. Chiodi, C. Kelly, R. Shattock, M. Chirenje, L. Lebina, S. Khoo, L-G Bekker, H. A. Weiss, C. Gray, L. Stranix-Chibanda, P. Kaleebu, J. Seeley, N. Martinson, J. Fox, on behalf of the CHAPS team
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Trials
Subjects:
HIV
PrEP
Uganda
South Africa
Zimbabwe
Adolescents
Online Access:http://link.springer.com/article/10.1186/s13063-020-04760-x

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