Prevalence and Antimicrobial Resistance Profile of Salmonella Isolated from Human, Animal and Environment Samples in South Asia: A 10-Year Meta-analysis
Abstract Salmonella is a foodborne zoonotic bacterium, and the antimicrobial-resistant strains of Salmonella are a worldwide health concern. Herein, we employed a meta-analysis to determine the pooled prevalence of Salmonella and its antimicrobial resistance status in human, animal, and environmenta...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2023-10-01
|
| Series: | Journal of Epidemiology and Global Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s44197-023-00160-x |
| _version_ | 1797416185611943936 |
|---|---|
| author | Himel Talukder Shamsul Alam Roky Konad Debnath Binayok Sharma Juned Ahmed Sawrab Roy |
| author_facet | Himel Talukder Shamsul Alam Roky Konad Debnath Binayok Sharma Juned Ahmed Sawrab Roy |
| author_sort | Himel Talukder |
| collection | DOAJ |
| description | Abstract Salmonella is a foodborne zoonotic bacterium, and the antimicrobial-resistant strains of Salmonella are a worldwide health concern. Herein, we employed a meta-analysis to determine the pooled prevalence of Salmonella and its antimicrobial resistance status in human, animal, and environmental isolates in South Asia. To this end, we followed the standard guideline of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statements for searching literature in three databases namely PubMed, Google Scholar, and CAB abstracts, and a total of 100 eligible datasets were finally included which were published from January 2010 to June 2021. In the pooled prevalence of Salmonella in South Asia, the random model effect was 14.47% (95% CI: 10.17–20.19) with a high degree of heterogeneity (I 2, 99.8%) and overall antimicrobial resistance was 70% (95% CI: 63.0–76.0) with a heterogeneity of 23.6%. The temporal distribution of the overall antimicrobial resistance (%) against Salmonella was increased from 53 to 77% within 10 years. Out of 18 distinct Salmonella serotypes, S. enterica was highly prevalent (14.22%, 95% CI: 4.02–39.64) followed by S. pullorum (13.50%, 95% CI: 5.64–29.93) with antimicrobial resistance (%) were 86.26 and 90.06, respectively. Noteworthy, nalidixic acid (74.25%) and tetracycline (37.64%) were found mostly resistant to Salmonella whereas ceftriaxone (1.07%) and cefixime (1.24%) were sensitive. This systematic review demonstrated that overall antibiotic resistance profiles of Salmonella are increasing over time in South Asia. Thus, adequate hygienic practices, proper use of antimicrobials, and implementation of antibiotic stewardship are imperative for halting the Salmonella spread and its antimicrobial resistance. |
| first_indexed | 2024-03-09T05:59:50Z |
| format | Article |
| id | doaj.art-02ee8e10c83e494ba2acc97efe9cff76 |
| institution | Directory Open Access Journal |
| issn | 2210-6014 |
| language | English |
| last_indexed | 2024-03-09T05:59:50Z |
| publishDate | 2023-10-01 |
| publisher | Springer |
| record_format | Article |
| series | Journal of Epidemiology and Global Health |
| spelling | doaj.art-02ee8e10c83e494ba2acc97efe9cff762023-12-03T12:09:22ZengSpringerJournal of Epidemiology and Global Health2210-60142023-10-0113463765210.1007/s44197-023-00160-xPrevalence and Antimicrobial Resistance Profile of Salmonella Isolated from Human, Animal and Environment Samples in South Asia: A 10-Year Meta-analysisHimel Talukder0Shamsul Alam Roky1Konad Debnath2Binayok Sharma3Juned Ahmed4Sawrab Roy5Department of Epidemiology and Public Health, Sylhet Agricultural UniversityDepartment of Dairy Science, Sylhet Agricultural UniversityDepartment of Epidemiology and Public Health, Sylhet Agricultural UniversityDepartment of Medicine, Sylhet Agricultural UniversityDepartment of Pathology, Sylhet Agricultural UniversityDepartment of Microbiology and Immunology, Sylhet Agricultural UniversityAbstract Salmonella is a foodborne zoonotic bacterium, and the antimicrobial-resistant strains of Salmonella are a worldwide health concern. Herein, we employed a meta-analysis to determine the pooled prevalence of Salmonella and its antimicrobial resistance status in human, animal, and environmental isolates in South Asia. To this end, we followed the standard guideline of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statements for searching literature in three databases namely PubMed, Google Scholar, and CAB abstracts, and a total of 100 eligible datasets were finally included which were published from January 2010 to June 2021. In the pooled prevalence of Salmonella in South Asia, the random model effect was 14.47% (95% CI: 10.17–20.19) with a high degree of heterogeneity (I 2, 99.8%) and overall antimicrobial resistance was 70% (95% CI: 63.0–76.0) with a heterogeneity of 23.6%. The temporal distribution of the overall antimicrobial resistance (%) against Salmonella was increased from 53 to 77% within 10 years. Out of 18 distinct Salmonella serotypes, S. enterica was highly prevalent (14.22%, 95% CI: 4.02–39.64) followed by S. pullorum (13.50%, 95% CI: 5.64–29.93) with antimicrobial resistance (%) were 86.26 and 90.06, respectively. Noteworthy, nalidixic acid (74.25%) and tetracycline (37.64%) were found mostly resistant to Salmonella whereas ceftriaxone (1.07%) and cefixime (1.24%) were sensitive. This systematic review demonstrated that overall antibiotic resistance profiles of Salmonella are increasing over time in South Asia. Thus, adequate hygienic practices, proper use of antimicrobials, and implementation of antibiotic stewardship are imperative for halting the Salmonella spread and its antimicrobial resistance.https://doi.org/10.1007/s44197-023-00160-xPrevalenceAntimicrobial resistanceSalmonellaSouth Asia |
| spellingShingle | Himel Talukder Shamsul Alam Roky Konad Debnath Binayok Sharma Juned Ahmed Sawrab Roy Prevalence and Antimicrobial Resistance Profile of Salmonella Isolated from Human, Animal and Environment Samples in South Asia: A 10-Year Meta-analysis Journal of Epidemiology and Global Health Prevalence Antimicrobial resistance Salmonella South Asia |
| title | Prevalence and Antimicrobial Resistance Profile of Salmonella Isolated from Human, Animal and Environment Samples in South Asia: A 10-Year Meta-analysis |
| title_full | Prevalence and Antimicrobial Resistance Profile of Salmonella Isolated from Human, Animal and Environment Samples in South Asia: A 10-Year Meta-analysis |
| title_fullStr | Prevalence and Antimicrobial Resistance Profile of Salmonella Isolated from Human, Animal and Environment Samples in South Asia: A 10-Year Meta-analysis |
| title_full_unstemmed | Prevalence and Antimicrobial Resistance Profile of Salmonella Isolated from Human, Animal and Environment Samples in South Asia: A 10-Year Meta-analysis |
| title_short | Prevalence and Antimicrobial Resistance Profile of Salmonella Isolated from Human, Animal and Environment Samples in South Asia: A 10-Year Meta-analysis |
| title_sort | prevalence and antimicrobial resistance profile of salmonella isolated from human animal and environment samples in south asia a 10 year meta analysis |
| topic | Prevalence Antimicrobial resistance Salmonella South Asia |
| url | https://doi.org/10.1007/s44197-023-00160-x |
| work_keys_str_mv | AT himeltalukder prevalenceandantimicrobialresistanceprofileofsalmonellaisolatedfromhumananimalandenvironmentsamplesinsouthasiaa10yearmetaanalysis AT shamsulalamroky prevalenceandantimicrobialresistanceprofileofsalmonellaisolatedfromhumananimalandenvironmentsamplesinsouthasiaa10yearmetaanalysis AT konaddebnath prevalenceandantimicrobialresistanceprofileofsalmonellaisolatedfromhumananimalandenvironmentsamplesinsouthasiaa10yearmetaanalysis AT binayoksharma prevalenceandantimicrobialresistanceprofileofsalmonellaisolatedfromhumananimalandenvironmentsamplesinsouthasiaa10yearmetaanalysis AT junedahmed prevalenceandantimicrobialresistanceprofileofsalmonellaisolatedfromhumananimalandenvironmentsamplesinsouthasiaa10yearmetaanalysis AT sawrabroy prevalenceandantimicrobialresistanceprofileofsalmonellaisolatedfromhumananimalandenvironmentsamplesinsouthasiaa10yearmetaanalysis |