Neuropsychiatric manifestations of monkeypox: A clinically oriented comprehensive review
Abstract Monkeypox (MPX) has emerged as a threatening outbreak in recent months. The understanding of disease pathogenesis and its systemic involvement has evolved with time. Both the virus and its vaccine, like other members of the Orthopoxvirus family, were always expected to have neuropsychiatric...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-04-01
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| Series: | Brain and Behavior |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/brb3.2934 |
| _version_ | 1797821190787563520 |
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| author | Yashendra Sethi Pratik Agarwal Hamsa Murli Summaiya Waheed Sajeda Ghassan Matar Mohamed Baklola Hitesh Chopra Talha Bin Emran Elfatih A. Hasabo |
| author_facet | Yashendra Sethi Pratik Agarwal Hamsa Murli Summaiya Waheed Sajeda Ghassan Matar Mohamed Baklola Hitesh Chopra Talha Bin Emran Elfatih A. Hasabo |
| author_sort | Yashendra Sethi |
| collection | DOAJ |
| description | Abstract Monkeypox (MPX) has emerged as a threatening outbreak in recent months. The understanding of disease pathogenesis and its systemic involvement has evolved with time. Both the virus and its vaccine, like other members of the Orthopoxvirus family, were always expected to have neuropsychiatric consequences. Several neurological complications have been reported with MPX and its vaccines that include but not limited to headaches, myalgia, encephalitis, and coma. Psychiatric complications like anxiety and depression have also been reported; however, we lack evidence to present a direct causality. We conducted a literature review to compile recent evidence on neuropsychiatric manifestations and underline the importance of evolving aspects and complications of MPX. We advocate for better reporting of cases and adverse events, to enhance our understanding of the disease, aiding physicians to make more informed decisions, thus facilitating timely diagnosis and treatment. |
| first_indexed | 2024-03-13T09:49:06Z |
| format | Article |
| id | doaj.art-02f0f7dcad194358bb88b603ff928de2 |
| institution | Directory Open Access Journal |
| issn | 2162-3279 |
| language | English |
| last_indexed | 2024-03-13T09:49:06Z |
| publishDate | 2023-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Brain and Behavior |
| spelling | doaj.art-02f0f7dcad194358bb88b603ff928de22023-05-24T14:27:20ZengWileyBrain and Behavior2162-32792023-04-01134n/an/a10.1002/brb3.2934Neuropsychiatric manifestations of monkeypox: A clinically oriented comprehensive reviewYashendra Sethi0Pratik Agarwal1Hamsa Murli2Summaiya Waheed3Sajeda Ghassan Matar4Mohamed Baklola5Hitesh Chopra6Talha Bin Emran7Elfatih A. Hasabo8Department of Medicine Government Doon Medical College Dehradun IndiaDepartment of Medicine Lokmanya Tilak Municipal Medical College Mumbai IndiaDepartment of Medicine Lokmanya Tilak Municipal Medical College Mumbai IndiaDepartment of Medicine Dow Medical College, Dow University Of Health Sciences Karachi PakistanFaculty of Pharmacy Applied Science Private University Amman JordanFaculty of medicine Mansoura University Mansoura EgyptChitkara College of Pharmacy Chitkara University Punjab IndiaDepartment of Pharmacy BGC Trust University Bangladesh Chittagong BangladeshFaculty of Medicine University of Khartoum Khartoum SudanAbstract Monkeypox (MPX) has emerged as a threatening outbreak in recent months. The understanding of disease pathogenesis and its systemic involvement has evolved with time. Both the virus and its vaccine, like other members of the Orthopoxvirus family, were always expected to have neuropsychiatric consequences. Several neurological complications have been reported with MPX and its vaccines that include but not limited to headaches, myalgia, encephalitis, and coma. Psychiatric complications like anxiety and depression have also been reported; however, we lack evidence to present a direct causality. We conducted a literature review to compile recent evidence on neuropsychiatric manifestations and underline the importance of evolving aspects and complications of MPX. We advocate for better reporting of cases and adverse events, to enhance our understanding of the disease, aiding physicians to make more informed decisions, thus facilitating timely diagnosis and treatment.https://doi.org/10.1002/brb3.2934monkeypoxMPXMPX vaccineneurological manifestationsoutbreakpsychiatric manifestations |
| spellingShingle | Yashendra Sethi Pratik Agarwal Hamsa Murli Summaiya Waheed Sajeda Ghassan Matar Mohamed Baklola Hitesh Chopra Talha Bin Emran Elfatih A. Hasabo Neuropsychiatric manifestations of monkeypox: A clinically oriented comprehensive review Brain and Behavior monkeypox MPX MPX vaccine neurological manifestations outbreak psychiatric manifestations |
| title | Neuropsychiatric manifestations of monkeypox: A clinically oriented comprehensive review |
| title_full | Neuropsychiatric manifestations of monkeypox: A clinically oriented comprehensive review |
| title_fullStr | Neuropsychiatric manifestations of monkeypox: A clinically oriented comprehensive review |
| title_full_unstemmed | Neuropsychiatric manifestations of monkeypox: A clinically oriented comprehensive review |
| title_short | Neuropsychiatric manifestations of monkeypox: A clinically oriented comprehensive review |
| title_sort | neuropsychiatric manifestations of monkeypox a clinically oriented comprehensive review |
| topic | monkeypox MPX MPX vaccine neurological manifestations outbreak psychiatric manifestations |
| url | https://doi.org/10.1002/brb3.2934 |
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