Magneto-Impedance Biosensor Sensitivity: Effect and Enhancement
Biosensors based on magneto-impedance (MI) effect are powerful tools for biomedical applications as they are highly sensitive, stable, exhibit fast response, small in size, and have low hysteresis and power consumption. However, the performance of these biosensors is influenced by a variety of facto...
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| Format: | Article |
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MDPI AG
2020-09-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/20/18/5213 |
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| author | Abkar Sayad Efstratios Skafidas Patrick Kwan |
| author_facet | Abkar Sayad Efstratios Skafidas Patrick Kwan |
| author_sort | Abkar Sayad |
| collection | DOAJ |
| description | Biosensors based on magneto-impedance (MI) effect are powerful tools for biomedical applications as they are highly sensitive, stable, exhibit fast response, small in size, and have low hysteresis and power consumption. However, the performance of these biosensors is influenced by a variety of factors, including the design, geometry, materials and fabrication procedures. Other less appreciated factors influencing the MI effect include measuring circuit implementation, the material used for construction, geometry of the thin film sensing element, and patterning shapes compatible with the interface microelectronic circuitry. The type magnetic (ferrofluid, Dynabeads, and nanoparticles) and size of the particles, the magnetic particle concentration, magnetic field strength and stray magnetic fields can also affect the sensor sensitivity. Based on these considerations it is proposed that ideal MI biosensor sensitivity could be achieved when the sensor is constructed in sandwich thick magnetic layers with large sensing area in a meander shape, measured with circuitry that provides the lowest possible external inductance at high frequencies, enclosed by a protective layer between magnetic particles and sensing element, and perpendicularly magnetized when detecting high-concentration of magnetic particles. |
| first_indexed | 2024-03-10T16:22:10Z |
| format | Article |
| id | doaj.art-02f19c853cea498387049cdd1dd15cb9 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-10T16:22:10Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-02f19c853cea498387049cdd1dd15cb92023-11-20T13:33:33ZengMDPI AGSensors1424-82202020-09-012018521310.3390/s20185213Magneto-Impedance Biosensor Sensitivity: Effect and EnhancementAbkar Sayad0Efstratios Skafidas1Patrick Kwan2Department of Neuroscience, The Alfred Centre, Central Clinical School, Monash University, Melbourne, Victoria 3004, AustraliaDepartment of Electrical and Electronic Engineering, Melbourne School of Engineering, The University of Melbourne, Victoria 3010, AustraliaDepartment of Neuroscience, The Alfred Centre, Central Clinical School, Monash University, Melbourne, Victoria 3004, AustraliaBiosensors based on magneto-impedance (MI) effect are powerful tools for biomedical applications as they are highly sensitive, stable, exhibit fast response, small in size, and have low hysteresis and power consumption. However, the performance of these biosensors is influenced by a variety of factors, including the design, geometry, materials and fabrication procedures. Other less appreciated factors influencing the MI effect include measuring circuit implementation, the material used for construction, geometry of the thin film sensing element, and patterning shapes compatible with the interface microelectronic circuitry. The type magnetic (ferrofluid, Dynabeads, and nanoparticles) and size of the particles, the magnetic particle concentration, magnetic field strength and stray magnetic fields can also affect the sensor sensitivity. Based on these considerations it is proposed that ideal MI biosensor sensitivity could be achieved when the sensor is constructed in sandwich thick magnetic layers with large sensing area in a meander shape, measured with circuitry that provides the lowest possible external inductance at high frequencies, enclosed by a protective layer between magnetic particles and sensing element, and perpendicularly magnetized when detecting high-concentration of magnetic particles.https://www.mdpi.com/1424-8220/20/18/5213magneto-impedanceimpedancemagnetic materialsmagnetic particlesbiosensorsensitivity |
| spellingShingle | Abkar Sayad Efstratios Skafidas Patrick Kwan Magneto-Impedance Biosensor Sensitivity: Effect and Enhancement Sensors magneto-impedance impedance magnetic materials magnetic particles biosensor sensitivity |
| title | Magneto-Impedance Biosensor Sensitivity: Effect and Enhancement |
| title_full | Magneto-Impedance Biosensor Sensitivity: Effect and Enhancement |
| title_fullStr | Magneto-Impedance Biosensor Sensitivity: Effect and Enhancement |
| title_full_unstemmed | Magneto-Impedance Biosensor Sensitivity: Effect and Enhancement |
| title_short | Magneto-Impedance Biosensor Sensitivity: Effect and Enhancement |
| title_sort | magneto impedance biosensor sensitivity effect and enhancement |
| topic | magneto-impedance impedance magnetic materials magnetic particles biosensor sensitivity |
| url | https://www.mdpi.com/1424-8220/20/18/5213 |
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