Utility of Cardiopulmonary Exercise Testing in Chronic Obstructive Pulmonary Disease: A Review
Mehrdad Behnia,1 Kathy E Sietsema2 1Pulmonary and Critical Care, University of Central Florida, Orlando, FL, USA; 2The Lundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Torrance, CA, USACorrespondence: Mehrdad Behnia, Pulmonary and Critical Care, University of Central Florid...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2023-12-01
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| Series: | International Journal of COPD |
| Subjects: | |
| Online Access: | https://www.dovepress.com/utility-of-cardiopulmonary-exercise-testing-in-chronic-obstructive-pul-peer-reviewed-fulltext-article-COPD |
| _version_ | 1827594962868371456 |
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| author | Behnia M Sietsema KE |
| author_facet | Behnia M Sietsema KE |
| author_sort | Behnia M |
| collection | DOAJ |
| description | Mehrdad Behnia,1 Kathy E Sietsema2 1Pulmonary and Critical Care, University of Central Florida, Orlando, FL, USA; 2The Lundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Torrance, CA, USACorrespondence: Mehrdad Behnia, Pulmonary and Critical Care, University of Central Florida, PO Box 953814, Lake Mary, FL, 32749, USA, Tel +1 706-339-8634, Email Mehrdad.behnia.md.phd@adventhelath.comAbstract: Chronic obstructive pulmonary disease (COPD) is a disease defined by airflow obstruction with a high morbidity and mortality and significant economic burden. Although pulmonary function testing is the cornerstone in diagnosis of COPD, it cannot fully characterize disease severity or cause of dyspnea because of disease heterogeneity and variable related and comorbid conditions affecting cardiac, vascular, and musculoskeletal systems. Cardiopulmonary exercise testing (CPET) is a valuable tool for assessing physical function in a wide range of clinical conditions, including COPD. Familiarity with measurements made during CPET and its potential to aid in clinical decision-making related to COPD can thus be useful to clinicians caring for this population. This review highlights pulmonary and extrapulmonary impairments that can contribute to exercise limitation in COPD. Key elements of CPET are identified with an emphasis on measurements most relevant to COPD. Finally, clinical applications of CPET demonstrated to be of value in the COPD setting are identified. These include quantifying functional capacity, differentiating among potential causes of symptoms and limitation, prognostication and risk assessment for operative procedures, and guiding exercise prescriptionKeywords: dyspnea, obstructive lung disease, exercise intolerance, exercise limitation |
| first_indexed | 2024-03-09T02:44:51Z |
| format | Article |
| id | doaj.art-02f455cd21634f8db52847d7114f4e3e |
| institution | Directory Open Access Journal |
| issn | 1178-2005 |
| language | English |
| last_indexed | 2024-03-09T02:44:51Z |
| publishDate | 2023-12-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of COPD |
| spelling | doaj.art-02f455cd21634f8db52847d7114f4e3e2023-12-05T17:06:55ZengDove Medical PressInternational Journal of COPD1178-20052023-12-01Volume 182895291088730Utility of Cardiopulmonary Exercise Testing in Chronic Obstructive Pulmonary Disease: A ReviewBehnia MSietsema KEMehrdad Behnia,1 Kathy E Sietsema2 1Pulmonary and Critical Care, University of Central Florida, Orlando, FL, USA; 2The Lundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Torrance, CA, USACorrespondence: Mehrdad Behnia, Pulmonary and Critical Care, University of Central Florida, PO Box 953814, Lake Mary, FL, 32749, USA, Tel +1 706-339-8634, Email Mehrdad.behnia.md.phd@adventhelath.comAbstract: Chronic obstructive pulmonary disease (COPD) is a disease defined by airflow obstruction with a high morbidity and mortality and significant economic burden. Although pulmonary function testing is the cornerstone in diagnosis of COPD, it cannot fully characterize disease severity or cause of dyspnea because of disease heterogeneity and variable related and comorbid conditions affecting cardiac, vascular, and musculoskeletal systems. Cardiopulmonary exercise testing (CPET) is a valuable tool for assessing physical function in a wide range of clinical conditions, including COPD. Familiarity with measurements made during CPET and its potential to aid in clinical decision-making related to COPD can thus be useful to clinicians caring for this population. This review highlights pulmonary and extrapulmonary impairments that can contribute to exercise limitation in COPD. Key elements of CPET are identified with an emphasis on measurements most relevant to COPD. Finally, clinical applications of CPET demonstrated to be of value in the COPD setting are identified. These include quantifying functional capacity, differentiating among potential causes of symptoms and limitation, prognostication and risk assessment for operative procedures, and guiding exercise prescriptionKeywords: dyspnea, obstructive lung disease, exercise intolerance, exercise limitationhttps://www.dovepress.com/utility-of-cardiopulmonary-exercise-testing-in-chronic-obstructive-pul-peer-reviewed-fulltext-article-COPDdyspneaobstructive lung diseaseexercise intoleranceexercise limitation |
| spellingShingle | Behnia M Sietsema KE Utility of Cardiopulmonary Exercise Testing in Chronic Obstructive Pulmonary Disease: A Review International Journal of COPD dyspnea obstructive lung disease exercise intolerance exercise limitation |
| title | Utility of Cardiopulmonary Exercise Testing in Chronic Obstructive Pulmonary Disease: A Review |
| title_full | Utility of Cardiopulmonary Exercise Testing in Chronic Obstructive Pulmonary Disease: A Review |
| title_fullStr | Utility of Cardiopulmonary Exercise Testing in Chronic Obstructive Pulmonary Disease: A Review |
| title_full_unstemmed | Utility of Cardiopulmonary Exercise Testing in Chronic Obstructive Pulmonary Disease: A Review |
| title_short | Utility of Cardiopulmonary Exercise Testing in Chronic Obstructive Pulmonary Disease: A Review |
| title_sort | utility of cardiopulmonary exercise testing in chronic obstructive pulmonary disease a review |
| topic | dyspnea obstructive lung disease exercise intolerance exercise limitation |
| url | https://www.dovepress.com/utility-of-cardiopulmonary-exercise-testing-in-chronic-obstructive-pul-peer-reviewed-fulltext-article-COPD |
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