Acral papular mucinosis: a new case of this rare entity

Abstract Acral persistent papular mucinosis (APPM) is a rare subtype of localized lichen myxedematosus. It consists of small papules localized exclusively on the back of the hands, wrists and extensor aspects of distal forearms with no other clinical or laboratory manifestations. The lesions tend to...

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Main Authors: María Encarnación Gómez Sánchez, Fernando de Manueles Marcos, Maria Luisa Martínez Martínez, Roberto Vera Berón, Jose Manuel Azaña Défez
Format: Article
Language:English
Published: Sociedade Brasileira de Dermatologia 2016-10-01
Series:Anais Brasileiros de Dermatologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016001100111&tlng=en
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author María Encarnación Gómez Sánchez
Fernando de Manueles Marcos
Maria Luisa Martínez Martínez
Roberto Vera Berón
Jose Manuel Azaña Défez
author_facet María Encarnación Gómez Sánchez
Fernando de Manueles Marcos
Maria Luisa Martínez Martínez
Roberto Vera Berón
Jose Manuel Azaña Défez
author_sort María Encarnación Gómez Sánchez
collection DOAJ
description Abstract Acral persistent papular mucinosis (APPM) is a rare subtype of localized lichen myxedematosus. It consists of small papules localized exclusively on the back of the hands, wrists and extensor aspects of distal forearms with no other clinical or laboratory manifestations. The lesions tend to persist and may increase slowly in number. Histologically, hematoxylin-eosin and Alcian blue staining demonstrate mucin accumulation in the upper reticular dermis with separation of collagen fibers as a result of hyaluronic acid deposition. Treatment is rarely necessary due to the absence of symptoms. We present a 27-year-old healthy woman with asymptomatic papules on her upper extremities, which adequately meet clinical and pathological criteria of acral papular mucinosis.
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spelling doaj.art-02fb65a2387d41c3b1d5aa3d407196872022-12-21T17:21:55ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962016-10-01915 suppl 111111310.1590/abd1806-4841.20164804Acral papular mucinosis: a new case of this rare entityMaría Encarnación Gómez SánchezFernando de Manueles MarcosMaria Luisa Martínez MartínezRoberto Vera BerónJose Manuel Azaña DéfezAbstract Acral persistent papular mucinosis (APPM) is a rare subtype of localized lichen myxedematosus. It consists of small papules localized exclusively on the back of the hands, wrists and extensor aspects of distal forearms with no other clinical or laboratory manifestations. The lesions tend to persist and may increase slowly in number. Histologically, hematoxylin-eosin and Alcian blue staining demonstrate mucin accumulation in the upper reticular dermis with separation of collagen fibers as a result of hyaluronic acid deposition. Treatment is rarely necessary due to the absence of symptoms. We present a 27-year-old healthy woman with asymptomatic papules on her upper extremities, which adequately meet clinical and pathological criteria of acral papular mucinosis.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016001100111&tlng=enMucinosesScleromyxedemaTherapeutics
spellingShingle María Encarnación Gómez Sánchez
Fernando de Manueles Marcos
Maria Luisa Martínez Martínez
Roberto Vera Berón
Jose Manuel Azaña Défez
Acral papular mucinosis: a new case of this rare entity
Anais Brasileiros de Dermatologia
Mucinoses
Scleromyxedema
Therapeutics
title Acral papular mucinosis: a new case of this rare entity
title_full Acral papular mucinosis: a new case of this rare entity
title_fullStr Acral papular mucinosis: a new case of this rare entity
title_full_unstemmed Acral papular mucinosis: a new case of this rare entity
title_short Acral papular mucinosis: a new case of this rare entity
title_sort acral papular mucinosis a new case of this rare entity
topic Mucinoses
Scleromyxedema
Therapeutics
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016001100111&tlng=en
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AT marialuisamartinezmartinez acralpapularmucinosisanewcaseofthisrareentity
AT robertoveraberon acralpapularmucinosisanewcaseofthisrareentity
AT josemanuelazanadefez acralpapularmucinosisanewcaseofthisrareentity