Clinical and Laboratory Manifestations of Meningococcemia in Children
Lack of vaccination and modern health care facilities in many countries including Iran let meningococcemia to remain as a serious challenging disorder especially among children and in spite of improved diagnosis and earlier treatment its prognosis is still dismal. This study describes 68 cases (54.4...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2006-08-01
|
| Series: | Iranian Journal of Public Health |
| Subjects: | |
| Online Access: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/2903.pdf&manuscript_id=2903 |
| _version_ | 1819102948322443264 |
|---|---|
| author | S Mamishi S Mostashfi habibabadi B Elahi |
| author_facet | S Mamishi S Mostashfi habibabadi B Elahi |
| author_sort | S Mamishi |
| collection | DOAJ |
| description | Lack of vaccination and modern health care facilities in many countries including Iran let meningococcemia to remain as a serious challenging disorder especially among children and in spite of improved diagnosis and earlier treatment its prognosis is still dismal. This study describes 68 cases (54.4% male) of proved meningococcemia hospitalized since 1992 up to the end of 2002 in Children Medical Center Hospital, Tehran, Iran. Infants of 6 to 12 month old were a major concern in number (14.7%) and severity of disease. 5.9% of the cases have had at least two hospitalization history for meningococcal septicemia and 19.1% of the patients had Systemic Lupus Erythematosus (SLE), nephrotic syndrome or chronic liver disease in their past medical history. Meningeal irritation signs were seen in 55.9% and cerebrospinal fluid (CSF) smear was positive in 71.4% and culture was positive in 48.5% of patients. Meningococcal septicemia ended in shock (38.2%), Disseminated intravascular coagulation (DIC) (7.4%), thrombocytopenia (10.3%), arthritis (4.4%),ocular complications (2.9%), pericarditis (2.9%) and seizure (8.8%) in 51 of the cases, and death occurred in 7 patients. This study shows that the manifestation of the disease is similar to those described elsewhere except for lower pneumonia and no seasonal variations. |
| first_indexed | 2024-12-22T01:42:40Z |
| format | Article |
| id | doaj.art-02fca49bc78a489488398dd3a320e227 |
| institution | Directory Open Access Journal |
| issn | 2251-6085 |
| language | English |
| last_indexed | 2024-12-22T01:42:40Z |
| publishDate | 2006-08-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Public Health |
| spelling | doaj.art-02fca49bc78a489488398dd3a320e2272022-12-21T18:43:09ZengTehran University of Medical SciencesIranian Journal of Public Health2251-60852006-08-013544953Clinical and Laboratory Manifestations of Meningococcemia in ChildrenS MamishiS Mostashfi habibabadiB ElahiLack of vaccination and modern health care facilities in many countries including Iran let meningococcemia to remain as a serious challenging disorder especially among children and in spite of improved diagnosis and earlier treatment its prognosis is still dismal. This study describes 68 cases (54.4% male) of proved meningococcemia hospitalized since 1992 up to the end of 2002 in Children Medical Center Hospital, Tehran, Iran. Infants of 6 to 12 month old were a major concern in number (14.7%) and severity of disease. 5.9% of the cases have had at least two hospitalization history for meningococcal septicemia and 19.1% of the patients had Systemic Lupus Erythematosus (SLE), nephrotic syndrome or chronic liver disease in their past medical history. Meningeal irritation signs were seen in 55.9% and cerebrospinal fluid (CSF) smear was positive in 71.4% and culture was positive in 48.5% of patients. Meningococcal septicemia ended in shock (38.2%), Disseminated intravascular coagulation (DIC) (7.4%), thrombocytopenia (10.3%), arthritis (4.4%),ocular complications (2.9%), pericarditis (2.9%) and seizure (8.8%) in 51 of the cases, and death occurred in 7 patients. This study shows that the manifestation of the disease is similar to those described elsewhere except for lower pneumonia and no seasonal variations.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/2903.pdf&manuscript_id=2903Neisseria meningitidesMeningococcemia |
| spellingShingle | S Mamishi S Mostashfi habibabadi B Elahi Clinical and Laboratory Manifestations of Meningococcemia in Children Iranian Journal of Public Health Neisseria meningitides Meningococcemia |
| title | Clinical and Laboratory Manifestations of Meningococcemia in Children |
| title_full | Clinical and Laboratory Manifestations of Meningococcemia in Children |
| title_fullStr | Clinical and Laboratory Manifestations of Meningococcemia in Children |
| title_full_unstemmed | Clinical and Laboratory Manifestations of Meningococcemia in Children |
| title_short | Clinical and Laboratory Manifestations of Meningococcemia in Children |
| title_sort | clinical and laboratory manifestations of meningococcemia in children |
| topic | Neisseria meningitides Meningococcemia |
| url | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/2903.pdf&manuscript_id=2903 |
| work_keys_str_mv | AT smamishi clinicalandlaboratorymanifestationsofmeningococcemiainchildren AT smostashfihabibabadi clinicalandlaboratorymanifestationsofmeningococcemiainchildren AT belahi clinicalandlaboratorymanifestationsofmeningococcemiainchildren |