Disruption of CSF2RA in the bovine preimplantation embryo reduces development and affects embryonic gene expression in utero

Disruption of CSF2RA in the bovine preimplantation embryo reduces development and affects embryonic gene expression in utero

The hypothesis that colony-stimulating factor 2 (CSF2) plays a role in the preimplantation development of the bovine embryo was tested by evaluating consequences of inactivation of CSF2RA (the functional receptor in the embryo) for the development of embryos in utero. CRISPR/Cas9 was used to alter s...

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Bibliographic Details
Main Authors: Froylan Sosa, Kyungjun Uh, Jéssica N Drum, Katy S Stoecklein, Kimberly M Davenport, M Sofia Ortega, Kiho Lee, Peter J Hansen
Format: Article
Language:English
Published: Bioscientifica 2023-05-01
Series:Reproduction and Fertility
Subjects:
csf2
preimplantation embryo
gene expression
csf2ra
Online Access:https://raf.bioscientifica.com/view/journals/raf/4/2/RAF-23-0001.xml

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