Administration of Parenteral Vitamin C in Patients With Severe Infection: Protocol for a Systematic Review and Meta-analysis

Administration of Parenteral Vitamin C in Patients With Severe Infection: Protocol for a Systematic Review and Meta-analysis

BackgroundSevere infections are characterized by inflammation and oxidative damage. Ascorbic acid (vitamin C) administration may attenuate oxidative damage and, in turn, reduce vascular endothelial injury in pulmonary and systemic vasculature. ObjectiveWe aim to d...

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Main Authors: Arnav Agarwal, John Basmaji, Shannon M Fernando, Fang Zhou Ge, Yingqi Xiao, Haseeb Faisal, Kimia Honarmand, Mathieu Hylands, Vincent I Lau, Kimberley Lewis, Rachel Couban, François Lamontagne, Neill KJ Adhikari
Format: Article
Language:English
Published: JMIR Publications 2022-01-01
Series:JMIR Research Protocols
Online Access:https://www.researchprotocols.org/2022/1/e33989

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