The d16HER2 Splice Variant: A Friend or Foe of HER2-Positive Cancers?

Human epidermal growth factor receptor 2 (<i>ERBB2</i> or HER2) amplification/overexpression is associated with a particularly aggressive molecular subtype of breast cancer (BC), characterized by a poor prognosis, increased metastatic potential, and disease recurrence. As only approximat...

Full description

Bibliographic Details
Main Authors: Lorenzo Castagnoli, Michael Ladomery, Elda Tagliabue, Serenella M. Pupa
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/7/902