Creating molecular macrocycles for anion recognition
The creation and functionality of new classes of macrocycles that are shape persistent and can bind anions is described. The genesis of triazolophane macrocycles emerges out of activity surrounding 1,2,3-triazoles made using click chemistry; and the same triazoles are responsible for anion capture....
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| Format: | Article |
| Language: | English |
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Beilstein-Institut
2016-03-01
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| Series: | Beilstein Journal of Organic Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.3762/bjoc.12.60 |
| _version_ | 1829514688594968576 |
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| author | Amar H. Flood |
| author_facet | Amar H. Flood |
| author_sort | Amar H. Flood |
| collection | DOAJ |
| description | The creation and functionality of new classes of macrocycles that are shape persistent and can bind anions is described. The genesis of triazolophane macrocycles emerges out of activity surrounding 1,2,3-triazoles made using click chemistry; and the same triazoles are responsible for anion capture. Mistakes made and lessons learnt in anion recognition provide deeper understanding that, together with theory, now provides for computer-aided receptor design. The lessons are acted upon in the creation of two new macrocycles. First, cyanostars are larger and like to capture large anions. Second is tricarb, which also favors large anions but shows a propensity to self-assemble in an orderly and stable manner, laying a foundation for future designs of hierarchical nanostructures. |
| first_indexed | 2024-12-16T13:22:02Z |
| format | Article |
| id | doaj.art-03082f826f6b48b6b31cef5c2cd45431 |
| institution | Directory Open Access Journal |
| issn | 1860-5397 |
| language | English |
| last_indexed | 2024-12-16T13:22:02Z |
| publishDate | 2016-03-01 |
| publisher | Beilstein-Institut |
| record_format | Article |
| series | Beilstein Journal of Organic Chemistry |
| spelling | doaj.art-03082f826f6b48b6b31cef5c2cd454312022-12-21T22:30:19ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972016-03-0112161162710.3762/bjoc.12.601860-5397-12-60Creating molecular macrocycles for anion recognitionAmar H. Flood0Department of Chemistry, Indiana University, Bloomington, IN 47405, USAThe creation and functionality of new classes of macrocycles that are shape persistent and can bind anions is described. The genesis of triazolophane macrocycles emerges out of activity surrounding 1,2,3-triazoles made using click chemistry; and the same triazoles are responsible for anion capture. Mistakes made and lessons learnt in anion recognition provide deeper understanding that, together with theory, now provides for computer-aided receptor design. The lessons are acted upon in the creation of two new macrocycles. First, cyanostars are larger and like to capture large anions. Second is tricarb, which also favors large anions but shows a propensity to self-assemble in an orderly and stable manner, laying a foundation for future designs of hierarchical nanostructures.https://doi.org/10.3762/bjoc.12.60anion receptors macrocycles self-assembly surface architectures switches |
| spellingShingle | Amar H. Flood Creating molecular macrocycles for anion recognition Beilstein Journal of Organic Chemistry anion receptors macrocycles self-assembly surface architectures switches |
| title | Creating molecular macrocycles for anion recognition |
| title_full | Creating molecular macrocycles for anion recognition |
| title_fullStr | Creating molecular macrocycles for anion recognition |
| title_full_unstemmed | Creating molecular macrocycles for anion recognition |
| title_short | Creating molecular macrocycles for anion recognition |
| title_sort | creating molecular macrocycles for anion recognition |
| topic | anion receptors macrocycles self-assembly surface architectures switches |
| url | https://doi.org/10.3762/bjoc.12.60 |
| work_keys_str_mv | AT amarhflood creatingmolecularmacrocyclesforanionrecognition |