Murine models to study human NK cells in human solid tumors

Murine models to study human NK cells in human solid tumors

Since the first studies, the mouse models have provided crucial support for the most important discoveries on NK cells, on their development, function, and circulation within normal and tumor tissues. Murine tumor models were initially set to study murine NK cells, then, ever more sophisticated huma...

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Bibliographic Details
Main Authors: Monica Parodi, Simonetta Astigiano, Paolo Carrega, Gabriella Pietra, Chiara Vitale, Laura Damele, Melania Grottoli, Maria de la Luz Guevara Lopez, Riccardo Ferracini, Giulia Bertolini, Ilaria Roato, Massimo Vitale, Paola Orecchia
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
natural killer cells
humanized mice
solid tumor
human-in-mouse model
tumor immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1209237/full

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