Azithromycin versus placebo for the treatment of HIV-associated chronic lung disease in children and adolescents (BREATHE trial): study protocol for a randomised controlled trial

Azithromycin versus placebo for the treatment of HIV-associated chronic lung disease in children and adolescents (BREATHE trial): study protocol for a randomised controlled trial

Abstract Background Human immunodeficiency virus (HIV)-related chronic lung disease (CLD) among children is associated with substantial morbidity, despite antiretroviral therapy. This may be a consequence of repeated respiratory tract infections and/or dysregulated immune activation that accompanies...

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Main Authors: Carmen Gonzalez-Martinez, Katharina Kranzer, Grace McHugh, Elizabeth L. Corbett, Hilda Mujuru, Mark P. Nicol, Sarah Rowland-Jones, Andrea M. Rehman, Tore J. Gutteberg, Trond Flaegstad, Jon O. Odland, Rashida A. Ferrand, the BREATHE study team
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Trials
Subjects:
Chronic lung disease
Azithromycin
HIV
FEV1
Africa
Children
Online Access:http://link.springer.com/article/10.1186/s13063-017-2344-2

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