DNA Methylation in Noncancerous Liver Tissues as Biomarker for Multicentric Occurrence of Hepatitis C Virus–Related Hepatocellular Carcinoma

DNA Methylation in Noncancerous Liver Tissues as Biomarker for Multicentric Occurrence of Hepatitis C Virus–Related Hepatocellular Carcinoma

Background and Aims: Hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC) progresses with a highly multicentric occurrence (MO) even after radical hepatectomy. Despite several efforts to clarify the pathogenesis of MO, the underlying molecular mechanism remains elusive. The aim of this stu...

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Bibliographic Details
Main Authors: Hiroyuki Suzuki, Hideki Iwamoto, Ken Yamamoto, Mai Tsukaguchi, Toru Nakamura, Atsutaka Masuda, Takahiko Sakaue, Toshimitsu Tanaka, Takashi Niizeki, Shusuke Okamura, Shigeo Shimose, Tomotake Shirono, Yu Noda, Naoki Kamachi, Ryoko Kuromatsu, Toru Hisaka, Hirohisa Yano, Hironori Koga, Takuji Torimura
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Gastro Hep Advances
Subjects:
Hepatocellular Carcinoma
DNA Methylation
Hepatitis C Virus
Multicentric Occurrence
Online Access:http://www.sciencedirect.com/science/article/pii/S2772572322000346

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