Activation of temperature-sensitive TRPV1-like receptors in ARC POMC neurons reduces food intake.

Activation of temperature-sensitive TRPV1-like receptors in ARC POMC neurons reduces food intake.

Proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARC) respond to numerous hormonal and neural signals, resulting in changes in food intake. Here, we demonstrate that ARC POMC neurons express capsaicin-sensitive transient receptor potential vanilloid 1 receptor (TRPV1)-l...

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Bibliographic Details
Main Authors: Jae Hoon Jeong, Dong Kun Lee, Shun-Mei Liu, Streamson C Chua, Gary J Schwartz, Young-Hwan Jo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-04-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC5915833?pdf=render

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