A novel swine model of ricin-induced acute respiratory distress syndrome

A novel swine model of ricin-induced acute respiratory distress syndrome

Pulmonary exposure to the plant toxin ricin leads to respiratory insufficiency and death. To date, in-depth study of acute respiratory distress syndrome (ARDS) following pulmonary exposure to toxins is hampered by the lack of an appropriate animal model. To this end, we established the pig as a larg...

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Bibliographic Details
Main Authors: Shahaf Katalan, Reut Falach, Amir Rosner, Michael Goldvaser, Tal Brosh-Nissimov, Ayana Dvir, Avi Mizrachi, Orr Goren, Barak Cohen, Yoav Gal, Anita Sapoznikov, Sharon Ehrlich, Tamar Sabo, Chanoch Kronman
Format: Article
Language:English
Published: The Company of Biologists 2017-02-01
Series:Disease Models & Mechanisms
Subjects:
Ricin
ARDS
Pig
Animal model
Lung permeability
Inflammation
Online Access:http://dmm.biologists.org/content/10/2/173

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