Aqueous Morinda citrifolia Leaves Extract Enhancing Glutathione Peroxidase Activity and α2-Macroglobulin Gene Expression on Macrobrachium rosenbergii
Morinda citrifolia, known commercially as noni is often used for enhancing immunity, these plant-rich phenolic compound with antioxidant properties. In the present study, Macrobrachium rosenbergii were fed diets containing aqueous M. citrifolia leaves extract (AMLE) at 0.6, 4 and 6 g kg-1. Glutathio...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
University of Brawijaya
2017-06-01
|
| Series: | Research Journal of Life Science |
| Subjects: | |
| Online Access: | http://rjls.ub.ac.id/index.php/rjls/article/view/149 |
| _version_ | 1828330118328614912 |
|---|---|
| author | Atika Marisa Halim Arief Prajitno |
| author_facet | Atika Marisa Halim Arief Prajitno |
| author_sort | Atika Marisa Halim |
| collection | DOAJ |
| description | Morinda citrifolia, known commercially as noni is often used for enhancing immunity, these plant-rich phenolic compound with antioxidant properties. In the present study, Macrobrachium rosenbergii were fed diets containing aqueous M. citrifolia leaves extract (AMLE) at 0.6, 4 and 6 g kg-1. Glutathione peroxidase (GPx) and α2-macroglubulin (α2-M) activity were conducted to measure an immune parameter, which was evaluated before and after 7, 21, 35, 49 and 63 days of feeding trial. The results showed that after 63 days of feeding treatment, significantly increased in GPx activity. Moreover, the gene expressions of α2-macroglubulin was significantly upregulated. These results recommend that administration of AMLE can be used as an immunostimulant and regulated immune response and immune gene expression in M. rosenbergii. |
| first_indexed | 2024-04-13T20:35:49Z |
| format | Article |
| id | doaj.art-03136f3ee1fb475f9bf93c46fc008bd0 |
| institution | Directory Open Access Journal |
| issn | 2355-9926 |
| language | English |
| last_indexed | 2024-04-13T20:35:49Z |
| publishDate | 2017-06-01 |
| publisher | University of Brawijaya |
| record_format | Article |
| series | Research Journal of Life Science |
| spelling | doaj.art-03136f3ee1fb475f9bf93c46fc008bd02022-12-22T02:31:03ZengUniversity of BrawijayaResearch Journal of Life Science2355-99262017-06-0141253310.21776/ub.rjls.2017.004.01.475Aqueous Morinda citrifolia Leaves Extract Enhancing Glutathione Peroxidase Activity and α2-Macroglobulin Gene Expression on Macrobrachium rosenbergiiAtika Marisa Halim0Arief Prajitno1Faculty of Fisheries and Marine Science, University of Brawijaya, IndonesiaFaculty of Fisheries and Marine Science, University of Brawijaya, IndonesiaMorinda citrifolia, known commercially as noni is often used for enhancing immunity, these plant-rich phenolic compound with antioxidant properties. In the present study, Macrobrachium rosenbergii were fed diets containing aqueous M. citrifolia leaves extract (AMLE) at 0.6, 4 and 6 g kg-1. Glutathione peroxidase (GPx) and α2-macroglubulin (α2-M) activity were conducted to measure an immune parameter, which was evaluated before and after 7, 21, 35, 49 and 63 days of feeding trial. The results showed that after 63 days of feeding treatment, significantly increased in GPx activity. Moreover, the gene expressions of α2-macroglubulin was significantly upregulated. These results recommend that administration of AMLE can be used as an immunostimulant and regulated immune response and immune gene expression in M. rosenbergii.http://rjls.ub.ac.id/index.php/rjls/article/view/149Morinda citrifoliaMacrobrachium rosenbergiiGPxα2-M |
| spellingShingle | Atika Marisa Halim Arief Prajitno Aqueous Morinda citrifolia Leaves Extract Enhancing Glutathione Peroxidase Activity and α2-Macroglobulin Gene Expression on Macrobrachium rosenbergii Research Journal of Life Science Morinda citrifolia Macrobrachium rosenbergii GPx α2-M |
| title | Aqueous Morinda citrifolia Leaves Extract Enhancing Glutathione Peroxidase Activity and α2-Macroglobulin Gene Expression on Macrobrachium rosenbergii |
| title_full | Aqueous Morinda citrifolia Leaves Extract Enhancing Glutathione Peroxidase Activity and α2-Macroglobulin Gene Expression on Macrobrachium rosenbergii |
| title_fullStr | Aqueous Morinda citrifolia Leaves Extract Enhancing Glutathione Peroxidase Activity and α2-Macroglobulin Gene Expression on Macrobrachium rosenbergii |
| title_full_unstemmed | Aqueous Morinda citrifolia Leaves Extract Enhancing Glutathione Peroxidase Activity and α2-Macroglobulin Gene Expression on Macrobrachium rosenbergii |
| title_short | Aqueous Morinda citrifolia Leaves Extract Enhancing Glutathione Peroxidase Activity and α2-Macroglobulin Gene Expression on Macrobrachium rosenbergii |
| title_sort | aqueous morinda citrifolia leaves extract enhancing glutathione peroxidase activity and α2 macroglobulin gene expression on macrobrachium rosenbergii |
| topic | Morinda citrifolia Macrobrachium rosenbergii GPx α2-M |
| url | http://rjls.ub.ac.id/index.php/rjls/article/view/149 |
| work_keys_str_mv | AT atikamarisahalim aqueousmorindacitrifolialeavesextractenhancingglutathioneperoxidaseactivityanda2macroglobulingeneexpressiononmacrobrachiumrosenbergii AT ariefprajitno aqueousmorindacitrifolialeavesextractenhancingglutathioneperoxidaseactivityanda2macroglobulingeneexpressiononmacrobrachiumrosenbergii |