Acute acalculous cholecystitis complicating chemotherapy for acute myeloblastic leukemia

Acute acalculous cholecystitis is a rare complication in the treatment of acute myeloblastic leukemia. Diagnosis of acute acalculous cholecystitis remains difficult during neutropenic period. We present two acute myeloblastic leukemia patients that developed acute acalculous cholecystitis during che...

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Main Authors: Olfa Kassar, Feten Kallel, Manel Ghorbel, Hatem Bellaaj, Zeineb Mnif, Moez Elloumi
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Leukemia Research Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213048915200374
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author Olfa Kassar
Feten Kallel
Manel Ghorbel
Hatem Bellaaj
Zeineb Mnif
Moez Elloumi
author_facet Olfa Kassar
Feten Kallel
Manel Ghorbel
Hatem Bellaaj
Zeineb Mnif
Moez Elloumi
author_sort Olfa Kassar
collection DOAJ
description Acute acalculous cholecystitis is a rare complication in the treatment of acute myeloblastic leukemia. Diagnosis of acute acalculous cholecystitis remains difficult during neutropenic period. We present two acute myeloblastic leukemia patients that developed acute acalculous cholecystitis during chemotherapy-induced neutropenia. They suffered from fever, vomiting and acute pain in the epigastrium. Ultrasound demonstrated an acalculous gallbladder. Surgical management was required in one patient and conservative treatment was attempted in the other patient. None treatment measures were effective and two patients died. Acute acalculous cholecystitis is a serious complication in neutropenic patients. Earlier diagnosis could have expedited the management of these patients.
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spelling doaj.art-03189fb95d684458ab6696aa46315dc42022-12-22T01:10:15ZengElsevierLeukemia Research Reports2213-04892015-01-0142394110.1016/j.lrr.2015.05.004Acute acalculous cholecystitis complicating chemotherapy for acute myeloblastic leukemiaOlfa Kassar0Feten Kallel1Manel Ghorbel2Hatem Bellaaj3Zeineb Mnif4Moez Elloumi5Department of Hematology, University of Sfax, Hedi Chaker Hospital, Sfax, TunisiaDepartment of Hematology, University of Sfax, Hedi Chaker Hospital, Sfax, TunisiaDepartment of Hematology, University of Sfax, Hedi Chaker Hospital, Sfax, TunisiaDepartment of Hematology, University of Sfax, Hedi Chaker Hospital, Sfax, TunisiaDepartment of Radiology, University of Sfax, Hedi Chaker Hospital, Sfax, TunisiaDepartment of Hematology, University of Sfax, Hedi Chaker Hospital, Sfax, TunisiaAcute acalculous cholecystitis is a rare complication in the treatment of acute myeloblastic leukemia. Diagnosis of acute acalculous cholecystitis remains difficult during neutropenic period. We present two acute myeloblastic leukemia patients that developed acute acalculous cholecystitis during chemotherapy-induced neutropenia. They suffered from fever, vomiting and acute pain in the epigastrium. Ultrasound demonstrated an acalculous gallbladder. Surgical management was required in one patient and conservative treatment was attempted in the other patient. None treatment measures were effective and two patients died. Acute acalculous cholecystitis is a serious complication in neutropenic patients. Earlier diagnosis could have expedited the management of these patients.http://www.sciencedirect.com/science/article/pii/S2213048915200374NeutropenicCholecystitisAcute leukemiaVoriconazoleChemotherapy
spellingShingle Olfa Kassar
Feten Kallel
Manel Ghorbel
Hatem Bellaaj
Zeineb Mnif
Moez Elloumi
Acute acalculous cholecystitis complicating chemotherapy for acute myeloblastic leukemia
Leukemia Research Reports
Neutropenic
Cholecystitis
Acute leukemia
Voriconazole
Chemotherapy
title Acute acalculous cholecystitis complicating chemotherapy for acute myeloblastic leukemia
title_full Acute acalculous cholecystitis complicating chemotherapy for acute myeloblastic leukemia
title_fullStr Acute acalculous cholecystitis complicating chemotherapy for acute myeloblastic leukemia
title_full_unstemmed Acute acalculous cholecystitis complicating chemotherapy for acute myeloblastic leukemia
title_short Acute acalculous cholecystitis complicating chemotherapy for acute myeloblastic leukemia
title_sort acute acalculous cholecystitis complicating chemotherapy for acute myeloblastic leukemia
topic Neutropenic
Cholecystitis
Acute leukemia
Voriconazole
Chemotherapy
url http://www.sciencedirect.com/science/article/pii/S2213048915200374
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