The role of AV and VV optimization for CRT
Cardiac resynchronization therapy is an effective therapy for patients with left ventricular systolic dysfunction and a ventricular conduction delay; however, approximately 30% of patients do not experience significant clinical improvement with this treatment. Modern devices allow individualized pro...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-06-01
|
| Series: | Journal of Arrhythmia |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1880427613000185 |
| _version_ | 1819022634073980928 |
|---|---|
| author | William W. Brabham, M.D. Michael R. Gold, M.D., Ph.D. |
| author_facet | William W. Brabham, M.D. Michael R. Gold, M.D., Ph.D. |
| author_sort | William W. Brabham, M.D. |
| collection | DOAJ |
| description | Cardiac resynchronization therapy is an effective therapy for patients with left ventricular systolic dysfunction and a ventricular conduction delay; however, approximately 30% of patients do not experience significant clinical improvement with this treatment. Modern devices allow individualized programming of the AV delay and VV offset, which offer the possibility of improving clinical response rates with optimized programming. AV and VV delay optimization techniques have included echocardiography, device-based algorithms, and several other novel noninvasive techniques. While an acute improvement in hemodynamic function has been clearly demonstrated with optimized device settings, long-term clinical benefit is limited. In the majority of cases, an empiric AV delay with simultaneous biventricular or left ventricular pacing is adequate. The value of optimization of these intervals in “non-responders” still requires further investigation. |
| first_indexed | 2024-12-21T04:26:07Z |
| format | Article |
| id | doaj.art-031dbdb9e5d0455e8d582671c77733e3 |
| institution | Directory Open Access Journal |
| issn | 1880-4276 |
| language | English |
| last_indexed | 2024-12-21T04:26:07Z |
| publishDate | 2013-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Arrhythmia |
| spelling | doaj.art-031dbdb9e5d0455e8d582671c77733e32022-12-21T19:16:03ZengWileyJournal of Arrhythmia1880-42762013-06-0129315316110.1016/j.joa.2013.02.001The role of AV and VV optimization for CRTWilliam W. Brabham, M.D.Michael R. Gold, M.D., Ph.D.Cardiac resynchronization therapy is an effective therapy for patients with left ventricular systolic dysfunction and a ventricular conduction delay; however, approximately 30% of patients do not experience significant clinical improvement with this treatment. Modern devices allow individualized programming of the AV delay and VV offset, which offer the possibility of improving clinical response rates with optimized programming. AV and VV delay optimization techniques have included echocardiography, device-based algorithms, and several other novel noninvasive techniques. While an acute improvement in hemodynamic function has been clearly demonstrated with optimized device settings, long-term clinical benefit is limited. In the majority of cases, an empiric AV delay with simultaneous biventricular or left ventricular pacing is adequate. The value of optimization of these intervals in “non-responders” still requires further investigation.http://www.sciencedirect.com/science/article/pii/S1880427613000185Cardiac resynchronization therapyOptimizationHeart failureImplantable defibrillatorAV delay |
| spellingShingle | William W. Brabham, M.D. Michael R. Gold, M.D., Ph.D. The role of AV and VV optimization for CRT Journal of Arrhythmia Cardiac resynchronization therapy Optimization Heart failure Implantable defibrillator AV delay |
| title | The role of AV and VV optimization for CRT |
| title_full | The role of AV and VV optimization for CRT |
| title_fullStr | The role of AV and VV optimization for CRT |
| title_full_unstemmed | The role of AV and VV optimization for CRT |
| title_short | The role of AV and VV optimization for CRT |
| title_sort | role of av and vv optimization for crt |
| topic | Cardiac resynchronization therapy Optimization Heart failure Implantable defibrillator AV delay |
| url | http://www.sciencedirect.com/science/article/pii/S1880427613000185 |
| work_keys_str_mv | AT williamwbrabhammd theroleofavandvvoptimizationforcrt AT michaelrgoldmdphd theroleofavandvvoptimizationforcrt AT williamwbrabhammd roleofavandvvoptimizationforcrt AT michaelrgoldmdphd roleofavandvvoptimizationforcrt |