COVID-19 Infection in Pediatric Patients: An Epidemiological Study in Iran
Background: COVID-19 is a highly infectious and contagious disease. Since the outbreak of COVID-19, most studies on children have focused on the incidence and prognosis of the disease, and few studies have investigated the epidemiological characteristics of the disease. Objectives: This study aimed...
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2022-01-01
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| Series: | Journal of Pediatrics Review |
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| Online Access: | http://jpr.mazums.ac.ir/article-1-396-en.html |
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| author | Maryam Naseri Gholamreza Khademi Majid Khadem Rezaeian Shahabaldin Sorouri Majid Sezavar |
| author_facet | Maryam Naseri Gholamreza Khademi Majid Khadem Rezaeian Shahabaldin Sorouri Majid Sezavar |
| author_sort | Maryam Naseri |
| collection | DOAJ |
| description | Background: COVID-19 is a highly infectious and contagious disease. Since the outbreak of COVID-19, most studies on children have focused on the incidence and prognosis of the disease, and few studies have investigated the epidemiological characteristics of the disease.
Objectives: This study aimed to investigate some epidemiological aspects of the disease in children with COVID-19.
Methods: We examined children with COVID-19 (under 18 years) hospitalized in the North East of Iran from the beginning of the outbreak until the end of September 2020. Study information was collected from patients’ medical records and interviews with their parents. We recorded demographic data; history of diseases and taking medicine in children; educational, occupational, and smoking status of parents; patients’ residence conditions; and any report of COVID-19 in patients’ families and relatives.
Results: Of 107 children studied, 57% were male, and 52.3% had no underlying disease. The mean age of patients was 67 months. The Mean±SD weight of the children was 20.36±13.75 kg, and their Mean±SD length of hospital stay was 9±8 days. Multisystem inflammatory syndrome in children (MIS-C) was observed in 34.6% of patients, and its relationship with death was highly significant (P=0.001). The length of hospital stay was influenced by the history of medication consumption (P=0.013) and underlying disease (P=0.001), and its increase was associated with an increased risk of MIS-C (P=0.032) and death (P=0.047).
Conclusions: Male sex, length of hospital stay, and MIS-C were identified as risk factors associated with worsening the outcome of COVID-19 disease in children. |
| first_indexed | 2024-04-12T17:02:58Z |
| format | Article |
| id | doaj.art-032647b367fa48a79df35c097cb9e85c |
| institution | Directory Open Access Journal |
| issn | 2322-4398 2322-4401 |
| language | English |
| last_indexed | 2024-04-12T17:02:58Z |
| publishDate | 2022-01-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Pediatrics Review |
| spelling | doaj.art-032647b367fa48a79df35c097cb9e85c2022-12-22T03:24:01ZengMazandaran University of Medical SciencesJournal of Pediatrics Review2322-43982322-44012022-01-0110Special Issue445454COVID-19 Infection in Pediatric Patients: An Epidemiological Study in IranMaryam Naseri0Gholamreza Khademi1Majid Khadem Rezaeian2Shahabaldin Sorouri3Majid Sezavar4 Department of Pediatrics, Mashhad University of Medical Sciences, Mashhad, Iran. Neonatal Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Clinical Research Development Unit of Akbar Hospital, Mashhad University of Medical Sciences, Mashhad, Iran. Internal Department, Mashhad University of Medical Sciences, Mashhad, Iran. Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Background: COVID-19 is a highly infectious and contagious disease. Since the outbreak of COVID-19, most studies on children have focused on the incidence and prognosis of the disease, and few studies have investigated the epidemiological characteristics of the disease. Objectives: This study aimed to investigate some epidemiological aspects of the disease in children with COVID-19. Methods: We examined children with COVID-19 (under 18 years) hospitalized in the North East of Iran from the beginning of the outbreak until the end of September 2020. Study information was collected from patients’ medical records and interviews with their parents. We recorded demographic data; history of diseases and taking medicine in children; educational, occupational, and smoking status of parents; patients’ residence conditions; and any report of COVID-19 in patients’ families and relatives. Results: Of 107 children studied, 57% were male, and 52.3% had no underlying disease. The mean age of patients was 67 months. The Mean±SD weight of the children was 20.36±13.75 kg, and their Mean±SD length of hospital stay was 9±8 days. Multisystem inflammatory syndrome in children (MIS-C) was observed in 34.6% of patients, and its relationship with death was highly significant (P=0.001). The length of hospital stay was influenced by the history of medication consumption (P=0.013) and underlying disease (P=0.001), and its increase was associated with an increased risk of MIS-C (P=0.032) and death (P=0.047). Conclusions: Male sex, length of hospital stay, and MIS-C were identified as risk factors associated with worsening the outcome of COVID-19 disease in children.http://jpr.mazums.ac.ir/article-1-396-en.htmlchildrencovid-19epidemiologymultisystem imis-csars-cov-2 |
| spellingShingle | Maryam Naseri Gholamreza Khademi Majid Khadem Rezaeian Shahabaldin Sorouri Majid Sezavar COVID-19 Infection in Pediatric Patients: An Epidemiological Study in Iran Journal of Pediatrics Review children covid-19 epidemiology multisystem imis-c sars-cov-2 |
| title | COVID-19 Infection in Pediatric Patients: An Epidemiological Study in Iran |
| title_full | COVID-19 Infection in Pediatric Patients: An Epidemiological Study in Iran |
| title_fullStr | COVID-19 Infection in Pediatric Patients: An Epidemiological Study in Iran |
| title_full_unstemmed | COVID-19 Infection in Pediatric Patients: An Epidemiological Study in Iran |
| title_short | COVID-19 Infection in Pediatric Patients: An Epidemiological Study in Iran |
| title_sort | covid 19 infection in pediatric patients an epidemiological study in iran |
| topic | children covid-19 epidemiology multisystem imis-c sars-cov-2 |
| url | http://jpr.mazums.ac.ir/article-1-396-en.html |
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