Outcomes of chronic dialysis in Korean children with respect to survival rates and causes of death
PurposeAdult Korean patients on chronic dialysis have a 9-year survival rate of 50%, with cardiovascular problems being the most significant cause of death. The 2011 annual report of the North American Pediatric Renal Trials and Collaborative Studies group reported 3-year survival rates of 93.4% and...
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| Format: | Article |
| Language: | English |
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Korean Pediatric Society
2014-03-01
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| Series: | Korean Journal of Pediatrics |
| Subjects: | |
| Online Access: | http://kjp.or.kr/upload/pdf/kjped-57-135.pdf |
| _version_ | 1819055314673074176 |
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| author | Hye Jin Chang Kyoung Hee Han Min Hyun Cho Young Seo Park Hee Gyung Kang Hae Il Cheong Il Soo Ha |
| author_facet | Hye Jin Chang Kyoung Hee Han Min Hyun Cho Young Seo Park Hee Gyung Kang Hae Il Cheong Il Soo Ha |
| author_sort | Hye Jin Chang |
| collection | DOAJ |
| description | PurposeAdult Korean patients on chronic dialysis have a 9-year survival rate of 50%, with cardiovascular problems being the most significant cause of death. The 2011 annual report of the North American Pediatric Renal Trials and Collaborative Studies group reported 3-year survival rates of 93.4% and relatively poorer survival in younger patients.MethodsIn this study, we have reviewed data from Korean Pediatric Chronic Kidney Disease Registry from 2002 to 2010 to assess survival rates and causes of death in Korean children on chronic dialysis.ResultsThe overall estimated patient survival rates were 98.4%, 94.4%, and 92.1% at 1, 3, and 5 years, respectively. No significant difference was observed in survival rates between patients on peritoneal dialysis and those on hemodialysis. Patients for whom dialysis was initiated before 2 years of age (n=40) had significantly lower survival rates than those for whom dialysis was initiated at 6-11 years of age (n=140). In all, 26 patients had died; the mortality rate was 19.9 per 1,000 patient years. The most common causes of death were infections and comorbidities such as malignancy and central nervous system (CNS) or liver diseases.ConclusionThe outcomes observed in this study were better than those observed in adults and comparable to those observed in pediatric studies in other countries. To improve the outcomes of children on chronic dialysis, it is necessary to prevent dialysis-related complications such as infection, congestive heart failure, or CNS hemorrhage and best control treatable comorbidities. |
| first_indexed | 2024-12-21T13:05:33Z |
| format | Article |
| id | doaj.art-032e515a809a44548ac91ef1c32124e5 |
| institution | Directory Open Access Journal |
| issn | 1738-1061 2092-7258 |
| language | English |
| last_indexed | 2024-12-21T13:05:33Z |
| publishDate | 2014-03-01 |
| publisher | Korean Pediatric Society |
| record_format | Article |
| series | Korean Journal of Pediatrics |
| spelling | doaj.art-032e515a809a44548ac91ef1c32124e52022-12-21T19:03:01ZengKorean Pediatric SocietyKorean Journal of Pediatrics1738-10612092-72582014-03-0157313513910.3345/kjp.2014.57.3.1352012600054Outcomes of chronic dialysis in Korean children with respect to survival rates and causes of deathHye Jin Chang0Kyoung Hee Han1Min Hyun Cho2Young Seo Park3Hee Gyung Kang4Hae Il Cheong5Il Soo Ha6Department of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.Department of Pediatrics, Jeju National University Hospital, Jeju, Korea.Department of Pediatrics, Kyungpook National University School of Medicine, Daegu, Korea.Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.Department of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.Department of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.Department of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.PurposeAdult Korean patients on chronic dialysis have a 9-year survival rate of 50%, with cardiovascular problems being the most significant cause of death. The 2011 annual report of the North American Pediatric Renal Trials and Collaborative Studies group reported 3-year survival rates of 93.4% and relatively poorer survival in younger patients.MethodsIn this study, we have reviewed data from Korean Pediatric Chronic Kidney Disease Registry from 2002 to 2010 to assess survival rates and causes of death in Korean children on chronic dialysis.ResultsThe overall estimated patient survival rates were 98.4%, 94.4%, and 92.1% at 1, 3, and 5 years, respectively. No significant difference was observed in survival rates between patients on peritoneal dialysis and those on hemodialysis. Patients for whom dialysis was initiated before 2 years of age (n=40) had significantly lower survival rates than those for whom dialysis was initiated at 6-11 years of age (n=140). In all, 26 patients had died; the mortality rate was 19.9 per 1,000 patient years. The most common causes of death were infections and comorbidities such as malignancy and central nervous system (CNS) or liver diseases.ConclusionThe outcomes observed in this study were better than those observed in adults and comparable to those observed in pediatric studies in other countries. To improve the outcomes of children on chronic dialysis, it is necessary to prevent dialysis-related complications such as infection, congestive heart failure, or CNS hemorrhage and best control treatable comorbidities.http://kjp.or.kr/upload/pdf/kjped-57-135.pdfSurvivalOutcomesEnd-stage renal diseaseDialysisChild |
| spellingShingle | Hye Jin Chang Kyoung Hee Han Min Hyun Cho Young Seo Park Hee Gyung Kang Hae Il Cheong Il Soo Ha Outcomes of chronic dialysis in Korean children with respect to survival rates and causes of death Korean Journal of Pediatrics Survival Outcomes End-stage renal disease Dialysis Child |
| title | Outcomes of chronic dialysis in Korean children with respect to survival rates and causes of death |
| title_full | Outcomes of chronic dialysis in Korean children with respect to survival rates and causes of death |
| title_fullStr | Outcomes of chronic dialysis in Korean children with respect to survival rates and causes of death |
| title_full_unstemmed | Outcomes of chronic dialysis in Korean children with respect to survival rates and causes of death |
| title_short | Outcomes of chronic dialysis in Korean children with respect to survival rates and causes of death |
| title_sort | outcomes of chronic dialysis in korean children with respect to survival rates and causes of death |
| topic | Survival Outcomes End-stage renal disease Dialysis Child |
| url | http://kjp.or.kr/upload/pdf/kjped-57-135.pdf |
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