Correlation of Lawsonia intracellularis positivity in quantitative PCR and herd factors in European pig herds
Abstract Background Lawsonia intracellularis is causing diarrhea, poor growth and sudden death in pigs. It can be found in most pig populations leading to large economic losses worldwide. Many potential risk factors for the occurrence of disease or seropositivity have been described. The current stu...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-01-01
|
| Series: | Porcine Health Management |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40813-021-00192-4 |
| _version_ | 1819055179295621120 |
|---|---|
| author | Mirjam Arnold Annelies Crienen Hanny Swam Stephan v. Berg Rika Jolie Heiko Nathues |
| author_facet | Mirjam Arnold Annelies Crienen Hanny Swam Stephan v. Berg Rika Jolie Heiko Nathues |
| author_sort | Mirjam Arnold |
| collection | DOAJ |
| description | Abstract Background Lawsonia intracellularis is causing diarrhea, poor growth and sudden death in pigs. It can be found in most pig populations leading to large economic losses worldwide. Many potential risk factors for the occurrence of disease or seropositivity have been described. The current study therefore focused on herd characteristics in European countries associated with direct detection of the pathogen determined by quantitative polymerase chain reaction. Results A median number of less than 30 nursery pigs per pen was correlated to less positive nursery pigs (p < 0.01) and generally less samples positive per herd (p < 0.05) as well as a lower median of genome equivalents determined per herd (p < 0.05). Routine use of zinc oxide at/ around weaning, which was mentioned by 41.0% of all farmers, was correlated to higher number of positive nursery pigs (p < 0.01) as well as higher median genome equivalents determined per herd (p < 0.05). Slatted flooring of more than 78.0% of the surface in nursery units was correlated to lower number of positive animals (p < 0.05) and a lower median of genome equivalents per herd (p < 0.05). A weight of more than 7.8 kg at weaning was correlated to a higher number of positive growing pigs (p < 0.05) as well as general higher number of positive samples/ herd (p < 0.01). Conclusions Weaning and subsequent accommodation of nursery pigs seem to be of particular importance in prevention of infection with Lawsonia intracellularis and the spread of the pathogen within the herd. |
| first_indexed | 2024-12-21T13:03:24Z |
| format | Article |
| id | doaj.art-032e680ecff548af90cb49cf14d6060f |
| institution | Directory Open Access Journal |
| issn | 2055-5660 |
| language | English |
| last_indexed | 2024-12-21T13:03:24Z |
| publishDate | 2021-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Porcine Health Management |
| spelling | doaj.art-032e680ecff548af90cb49cf14d6060f2022-12-21T19:03:06ZengBMCPorcine Health Management2055-56602021-01-01711810.1186/s40813-021-00192-4Correlation of Lawsonia intracellularis positivity in quantitative PCR and herd factors in European pig herdsMirjam Arnold0Annelies Crienen1Hanny Swam2Stephan v. Berg3Rika Jolie4Heiko Nathues5Clinic for Swine, Department for Clinical Veterinary Medicine, Vetsuisse Faculty, University of BernCenter for Diagnostic Solutions, MSD AH BoxmeerCenter for Diagnostic Solutions, MSD AH BoxmeerMSD Animal HealthMerck Animal HealthClinic for Swine, Department for Clinical Veterinary Medicine, Vetsuisse Faculty, University of BernAbstract Background Lawsonia intracellularis is causing diarrhea, poor growth and sudden death in pigs. It can be found in most pig populations leading to large economic losses worldwide. Many potential risk factors for the occurrence of disease or seropositivity have been described. The current study therefore focused on herd characteristics in European countries associated with direct detection of the pathogen determined by quantitative polymerase chain reaction. Results A median number of less than 30 nursery pigs per pen was correlated to less positive nursery pigs (p < 0.01) and generally less samples positive per herd (p < 0.05) as well as a lower median of genome equivalents determined per herd (p < 0.05). Routine use of zinc oxide at/ around weaning, which was mentioned by 41.0% of all farmers, was correlated to higher number of positive nursery pigs (p < 0.01) as well as higher median genome equivalents determined per herd (p < 0.05). Slatted flooring of more than 78.0% of the surface in nursery units was correlated to lower number of positive animals (p < 0.05) and a lower median of genome equivalents per herd (p < 0.05). A weight of more than 7.8 kg at weaning was correlated to a higher number of positive growing pigs (p < 0.05) as well as general higher number of positive samples/ herd (p < 0.01). Conclusions Weaning and subsequent accommodation of nursery pigs seem to be of particular importance in prevention of infection with Lawsonia intracellularis and the spread of the pathogen within the herd.https://doi.org/10.1186/s40813-021-00192-4ControlEuropePorcine proliferative enteropathyRisk factorSwine |
| spellingShingle | Mirjam Arnold Annelies Crienen Hanny Swam Stephan v. Berg Rika Jolie Heiko Nathues Correlation of Lawsonia intracellularis positivity in quantitative PCR and herd factors in European pig herds Porcine Health Management Control Europe Porcine proliferative enteropathy Risk factor Swine |
| title | Correlation of Lawsonia intracellularis positivity in quantitative PCR and herd factors in European pig herds |
| title_full | Correlation of Lawsonia intracellularis positivity in quantitative PCR and herd factors in European pig herds |
| title_fullStr | Correlation of Lawsonia intracellularis positivity in quantitative PCR and herd factors in European pig herds |
| title_full_unstemmed | Correlation of Lawsonia intracellularis positivity in quantitative PCR and herd factors in European pig herds |
| title_short | Correlation of Lawsonia intracellularis positivity in quantitative PCR and herd factors in European pig herds |
| title_sort | correlation of lawsonia intracellularis positivity in quantitative pcr and herd factors in european pig herds |
| topic | Control Europe Porcine proliferative enteropathy Risk factor Swine |
| url | https://doi.org/10.1186/s40813-021-00192-4 |
| work_keys_str_mv | AT mirjamarnold correlationoflawsoniaintracellularispositivityinquantitativepcrandherdfactorsineuropeanpigherds AT anneliescrienen correlationoflawsoniaintracellularispositivityinquantitativepcrandherdfactorsineuropeanpigherds AT hannyswam correlationoflawsoniaintracellularispositivityinquantitativepcrandherdfactorsineuropeanpigherds AT stephanvberg correlationoflawsoniaintracellularispositivityinquantitativepcrandherdfactorsineuropeanpigherds AT rikajolie correlationoflawsoniaintracellularispositivityinquantitativepcrandherdfactorsineuropeanpigherds AT heikonathues correlationoflawsoniaintracellularispositivityinquantitativepcrandherdfactorsineuropeanpigherds |