Does clozapine really affect bone mineral density? An experimental study

Does clozapine really affect bone mineral density? An experimental study

Abstract Purpose The aim of this study was to investigate the effect of clozapine use on bone tissue by applying computerized tomography, dual-energy X-ray absorptiometry, and histological and biomechanical analyses in an experimental rat model. Methods Sixteen female Wistar Albino rats were include...

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Bibliographic Details
Main Authors: Bahattin Kerem Aydin, Selim Safali, Memduha Aydin, Umran Egilmez, Hakan Cebeci, Murat Çelik, Ummuhan Abdulrezzak
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Osteoporosis
Schizophrenia
Rat
Bone mineral density
Clozapine
Online Access:https://doi.org/10.1186/s13018-021-02695-w

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