A new mouse model to study the role of ectopic Nanos3 expression in cancer

A new mouse model to study the role of ectopic Nanos3 expression in cancer

Abstract Background NANOS3 is a gene conserved throughout evolution. Despite the quite low conservation of Nanos sequences between different organisms and even between Nanos paralogs, their role in germ cell development is remarkably universal. Human Nanos3 expression is normally restricted to the g...

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Bibliographic Details
Main Authors: Vanessa Andries, Evi De Keuckelaere, Katrien Staes, Tino Hochepied, Joachim Taminau, Kelly Lemeire, Philippe Birembaut, Geert Berx, Frans van Roy
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Cancer
Subjects:
NANOS
Cre-loxP
ROSA26 locus
Mouse embryogenesis
Lung cancer model
Online Access:http://link.springer.com/article/10.1186/s12885-019-5807-x

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