A rare hematological complication of visceral leishmaniasis: hemophagocytic syndrome

The term “hemophagocytosis” describes the pathologic finding of activated macrophages, engulfing erythrocytes, leukocytes, platelets and their precursor cells. This phenomenon is an important finding in patients with hemophagocytic syndrome. It is a distinct clinical entity characterized by fever, p...

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Main Authors: Can Boğa, İlknur Kozanoğlu, Soner Solmaz, Süheyl Asma, Tuba Turunç, Yusuf Demiroğlu
Format: Article
Language:English
Published: Cukurova University 2016-03-01
Series:Cukurova Medical Journal
Online Access:https://dergipark.org.tr/tr/download/article-file/206058
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author Can Boğa
İlknur Kozanoğlu
Soner Solmaz
Süheyl Asma
Tuba Turunç
Yusuf Demiroğlu
author_facet Can Boğa
İlknur Kozanoğlu
Soner Solmaz
Süheyl Asma
Tuba Turunç
Yusuf Demiroğlu
author_sort Can Boğa
collection DOAJ
description The term “hemophagocytosis” describes the pathologic finding of activated macrophages, engulfing erythrocytes, leukocytes, platelets and their precursor cells. This phenomenon is an important finding in patients with hemophagocytic syndrome. It is a distinct clinical entity characterized by fever, pancytopenia, splenomegaly and hemophagocytosis in bone marrow, liver and lymph nodes. Hemophagocytic syndrome can be classified according to the underlying etiology into either primary (genetic) or secondary (acquired). Severe infections, malignancies, rheumatologic disorders and some metabolic diseases can lead to secondary hemophagocytic syndrome. Infection-associated hemophagocytic syndrome implicating Leishmania is very rare and often difficult to diagnose. Therefore, we aimed to report a young boy with Visceral Leishmaniasis associated hemophagocytic syndrome.
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spelling doaj.art-0331fbf40d094e089a3d617a66ced6252023-02-15T16:14:10ZengCukurova UniversityCukurova Medical Journal2602-30402016-03-0141116116348A rare hematological complication of visceral leishmaniasis: hemophagocytic syndromeCan Boğaİlknur KozanoğluSoner SolmazSüheyl AsmaTuba TurunçYusuf DemiroğluThe term “hemophagocytosis” describes the pathologic finding of activated macrophages, engulfing erythrocytes, leukocytes, platelets and their precursor cells. This phenomenon is an important finding in patients with hemophagocytic syndrome. It is a distinct clinical entity characterized by fever, pancytopenia, splenomegaly and hemophagocytosis in bone marrow, liver and lymph nodes. Hemophagocytic syndrome can be classified according to the underlying etiology into either primary (genetic) or secondary (acquired). Severe infections, malignancies, rheumatologic disorders and some metabolic diseases can lead to secondary hemophagocytic syndrome. Infection-associated hemophagocytic syndrome implicating Leishmania is very rare and often difficult to diagnose. Therefore, we aimed to report a young boy with Visceral Leishmaniasis associated hemophagocytic syndrome.https://dergipark.org.tr/tr/download/article-file/206058
spellingShingle Can Boğa
İlknur Kozanoğlu
Soner Solmaz
Süheyl Asma
Tuba Turunç
Yusuf Demiroğlu
A rare hematological complication of visceral leishmaniasis: hemophagocytic syndrome
Cukurova Medical Journal
title A rare hematological complication of visceral leishmaniasis: hemophagocytic syndrome
title_full A rare hematological complication of visceral leishmaniasis: hemophagocytic syndrome
title_fullStr A rare hematological complication of visceral leishmaniasis: hemophagocytic syndrome
title_full_unstemmed A rare hematological complication of visceral leishmaniasis: hemophagocytic syndrome
title_short A rare hematological complication of visceral leishmaniasis: hemophagocytic syndrome
title_sort rare hematological complication of visceral leishmaniasis hemophagocytic syndrome
url https://dergipark.org.tr/tr/download/article-file/206058
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