Improvement in both severe obsessive–compulsive disorder and refractory tardive dystonia following electroconvulsive therapy: A case report
Abstract Background Obsessive–compulsive disorder (OCD) is often resistant to treatment and may be complicated by tardive dystonia (TDt) with the use of neuroleptics. Furthermore, patients with TDt often have an inadequate response to pharmacotherapy. Although electroconvulsive therapy (ECT) is cons...
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| Format: | Article |
| Language: | English |
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Wiley
2022-06-01
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| Series: | PCN Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/pcn5.15 |
| _version_ | 1811183702825238528 |
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| author | Yasuha Mihara Koji Otsuki Mai Hayashi Satoko Yamashita Michiharu Nagahama Maiko Hayashida Rei Wake Sadayuki Hashioka Satoshi Abe Masatoshi Inagaki |
| author_facet | Yasuha Mihara Koji Otsuki Mai Hayashi Satoko Yamashita Michiharu Nagahama Maiko Hayashida Rei Wake Sadayuki Hashioka Satoshi Abe Masatoshi Inagaki |
| author_sort | Yasuha Mihara |
| collection | DOAJ |
| description | Abstract Background Obsessive–compulsive disorder (OCD) is often resistant to treatment and may be complicated by tardive dystonia (TDt) with the use of neuroleptics. Furthermore, patients with TDt often have an inadequate response to pharmacotherapy. Although electroconvulsive therapy (ECT) is considered a common treatment option for both TDt and OCD, its efficacy has not been well established for either condition. Case Presentation Our case was a 37‐year‐old Japanese woman who showed improvement in both refractory TDt and severe OCD following ECT. A total of 12 ECT sessions resulted in an improvement in both diseases. To the best of our knowledge, this is the first report of a case in which ECT was effective for both TDt and OCD. Conclusion Our report highlights the following two points: when TDt is associated with severe OCD, and the effect of pharmacotherapy is inadequate, ECT may be considered as a treatment option; given the common mechanism of frontal cortex‐basal dysfunction reported in both dystonia and OCD, ECT may have an effect on this pathway. |
| first_indexed | 2024-04-11T09:51:25Z |
| format | Article |
| id | doaj.art-0333a7dc5c4a449eaa4d44080a08548d |
| institution | Directory Open Access Journal |
| issn | 2769-2558 |
| language | English |
| last_indexed | 2024-04-11T09:51:25Z |
| publishDate | 2022-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | PCN Reports |
| spelling | doaj.art-0333a7dc5c4a449eaa4d44080a08548d2022-12-22T04:30:47ZengWileyPCN Reports2769-25582022-06-0112n/an/a10.1002/pcn5.15Improvement in both severe obsessive–compulsive disorder and refractory tardive dystonia following electroconvulsive therapy: A case reportYasuha Mihara0Koji Otsuki1Mai Hayashi2Satoko Yamashita3Michiharu Nagahama4Maiko Hayashida5Rei Wake6Sadayuki Hashioka7Satoshi Abe8Masatoshi Inagaki9Department of Psychiatry, Faculty of Medicine Shimane University Izumo JapanDepartment of Psychiatry, Faculty of Medicine Shimane University Izumo JapanDepartment of Psychiatry, Faculty of Medicine Shimane University Izumo JapanDepartment of Psychiatry, Faculty of Medicine Shimane University Izumo JapanDepartment of Psychiatry, Faculty of Medicine Shimane University Izumo JapanDepartment of Psychiatry, Faculty of Medicine Shimane University Izumo JapanDepartment of Psychiatry, Faculty of Medicine Shimane University Izumo JapanDepartment of Psychiatry, Faculty of Medicine Shimane University Izumo JapanDepartment of Neurology, Faculty of Medicine Shimane University Izumo JapanDepartment of Psychiatry, Faculty of Medicine Shimane University Izumo JapanAbstract Background Obsessive–compulsive disorder (OCD) is often resistant to treatment and may be complicated by tardive dystonia (TDt) with the use of neuroleptics. Furthermore, patients with TDt often have an inadequate response to pharmacotherapy. Although electroconvulsive therapy (ECT) is considered a common treatment option for both TDt and OCD, its efficacy has not been well established for either condition. Case Presentation Our case was a 37‐year‐old Japanese woman who showed improvement in both refractory TDt and severe OCD following ECT. A total of 12 ECT sessions resulted in an improvement in both diseases. To the best of our knowledge, this is the first report of a case in which ECT was effective for both TDt and OCD. Conclusion Our report highlights the following two points: when TDt is associated with severe OCD, and the effect of pharmacotherapy is inadequate, ECT may be considered as a treatment option; given the common mechanism of frontal cortex‐basal dysfunction reported in both dystonia and OCD, ECT may have an effect on this pathway.https://doi.org/10.1002/pcn5.15electroconvulsive therapyobsessive–compulsive disordertardive dystonia |
| spellingShingle | Yasuha Mihara Koji Otsuki Mai Hayashi Satoko Yamashita Michiharu Nagahama Maiko Hayashida Rei Wake Sadayuki Hashioka Satoshi Abe Masatoshi Inagaki Improvement in both severe obsessive–compulsive disorder and refractory tardive dystonia following electroconvulsive therapy: A case report PCN Reports electroconvulsive therapy obsessive–compulsive disorder tardive dystonia |
| title | Improvement in both severe obsessive–compulsive disorder and refractory tardive dystonia following electroconvulsive therapy: A case report |
| title_full | Improvement in both severe obsessive–compulsive disorder and refractory tardive dystonia following electroconvulsive therapy: A case report |
| title_fullStr | Improvement in both severe obsessive–compulsive disorder and refractory tardive dystonia following electroconvulsive therapy: A case report |
| title_full_unstemmed | Improvement in both severe obsessive–compulsive disorder and refractory tardive dystonia following electroconvulsive therapy: A case report |
| title_short | Improvement in both severe obsessive–compulsive disorder and refractory tardive dystonia following electroconvulsive therapy: A case report |
| title_sort | improvement in both severe obsessive compulsive disorder and refractory tardive dystonia following electroconvulsive therapy a case report |
| topic | electroconvulsive therapy obsessive–compulsive disorder tardive dystonia |
| url | https://doi.org/10.1002/pcn5.15 |
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