PK-PD integration of enrofloxacin and cefquinome alone and in combination against Klebsiella pneumoniae using an in vitro dynamic model

PK-PD integration of enrofloxacin and cefquinome alone and in combination against Klebsiella pneumoniae using an in vitro dynamic model

Introduction:Klebsiella pneumoniae is classified as a critical pathogen in both animals and humans and infections can be fatal in chickens resulting in substantial economic losses. However, the misuse of antibiotics can also lead to drug resistance and a potential transmission chain between animals...

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Bibliographic Details
Main Authors: Yanzhe Wei, Xuan Ji, Fuhui Zhang, Suiling Zhang, Qin Deng, Huanzhong Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Pharmacology
Subjects:
enrofloxacin
cefquinome
combination therapy
PK/PD model
Klebsiella pneumoniae
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1226936/full

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