Additively manufactured test phantoms for mimicking soft tissue radiation attenuation in CBCT using Polyjet technology
Objectives: To develop and validate a simple approach for building cost-effective imaging phantoms for Cone Beam Computed Tomography (CBCT) using a modified Polyjet additive manufacturing technology where a single material can mimic a range of human soft-tissue radiation attenuation. Materials and M...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-05-01
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| Series: | Zeitschrift für Medizinische Physik |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0939388922000630 |
| _version_ | 1797385259271061504 |
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| author | Sepideh Hatamikia Gunpreet Oberoi Anna Zacher Gernot Kronreif Wolfgang Birkfellner Joachim Kettenbach Stefanie Ponti Andrea Lorenz Martin Buschmann Laszlo Jaksa Nikolaus Irnstorfer Ewald Unger |
| author_facet | Sepideh Hatamikia Gunpreet Oberoi Anna Zacher Gernot Kronreif Wolfgang Birkfellner Joachim Kettenbach Stefanie Ponti Andrea Lorenz Martin Buschmann Laszlo Jaksa Nikolaus Irnstorfer Ewald Unger |
| author_sort | Sepideh Hatamikia |
| collection | DOAJ |
| description | Objectives: To develop and validate a simple approach for building cost-effective imaging phantoms for Cone Beam Computed Tomography (CBCT) using a modified Polyjet additive manufacturing technology where a single material can mimic a range of human soft-tissue radiation attenuation. Materials and Methods: Single material test phantoms using a cubic lattice were designed in 3-Matic 15.0 software . Keeping the individual cubic lattice volume constant, eight different percentage ratio (R) of air: material from 0% to 70% with a 10% increment were assigned to each sample. The phantoms were printed in three materials, namely Vero PureWhite, VeroClear and TangoPlus using Polyjet technology. The CT value analysis, non-contact profile measurement and microCT-based volumetric analysis was performed for all the samples. Results: The printed test phantoms produced a grey value spectrum equivalent to the radiation attenuation of human soft tissues in the range of −757 to +286 HU on CT. The results from dimensional comparison analysis of the printed phantoms with the digital test phantoms using non-contact profile measurement showed a mean accuracy of 99.07 % and that of micro-CT volumetric analysis showed mean volumetric accuracy of 84.80–94.91%. The material and printing costs of developing 24 test phantoms was 83.00 Euro. Conclusions: The study shows that additive manufacturing-guided macrostructure manipulation modifies successfully the radiographic visibility of a material in CBCT imaging with 1 mm3 resolution, helping customization of imaging phantoms. |
| first_indexed | 2024-03-08T21:51:40Z |
| format | Article |
| id | doaj.art-0334c42f9766412e94ea361fc0cdf32b |
| institution | Directory Open Access Journal |
| issn | 0939-3889 |
| language | English |
| last_indexed | 2024-03-08T21:51:40Z |
| publishDate | 2023-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Zeitschrift für Medizinische Physik |
| spelling | doaj.art-0334c42f9766412e94ea361fc0cdf32b2023-12-20T07:33:20ZengElsevierZeitschrift für Medizinische Physik0939-38892023-05-01332168181Additively manufactured test phantoms for mimicking soft tissue radiation attenuation in CBCT using Polyjet technologySepideh Hatamikia0Gunpreet Oberoi1Anna Zacher2Gernot Kronreif3Wolfgang Birkfellner4Joachim Kettenbach5Stefanie Ponti6Andrea Lorenz7Martin Buschmann8Laszlo Jaksa9Nikolaus Irnstorfer10Ewald Unger11Austrian Center for Medical Innovation and Technology (ACMIT), Wiener Neustadt, Austria; Research center for Medical Image Analysis and Artificial Intelligence (MIAAI), Department of Medicine, Faculty of Medicine and Dentistry, Danube Private University, Krems, Austria; Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria; Corresponding author: Sepideh Hatamikia, Austrian Center for Medical Innovation and Technology (ACMIT), Wiener Neustadt, Austria.Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, AustriaPreclinical Imaging Lab (PIL), Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, AustriaAustrian Center for Medical Innovation and Technology (ACMIT), Wiener Neustadt, AustriaCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, AustriaInstitute of Diagnostic, Interventional Radiology and Nuclear Medicine, Landesklinikum Wiener Neustadt, Wiener Neustadt, AustriaPreclinical Imaging Lab (PIL), Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, AustriaAustrian Center for Medical Innovation and Technology (ACMIT), Wiener Neustadt, AustriaDepartment of Radiation Oncology, Medical University of Vienna, Vienna, AustriaAustrian Center for Medical Innovation and Technology (ACMIT), Wiener Neustadt, AustriaDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy at the Medical University of Vienna, Vienna, AustriaCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, AustriaObjectives: To develop and validate a simple approach for building cost-effective imaging phantoms for Cone Beam Computed Tomography (CBCT) using a modified Polyjet additive manufacturing technology where a single material can mimic a range of human soft-tissue radiation attenuation. Materials and Methods: Single material test phantoms using a cubic lattice were designed in 3-Matic 15.0 software . Keeping the individual cubic lattice volume constant, eight different percentage ratio (R) of air: material from 0% to 70% with a 10% increment were assigned to each sample. The phantoms were printed in three materials, namely Vero PureWhite, VeroClear and TangoPlus using Polyjet technology. The CT value analysis, non-contact profile measurement and microCT-based volumetric analysis was performed for all the samples. Results: The printed test phantoms produced a grey value spectrum equivalent to the radiation attenuation of human soft tissues in the range of −757 to +286 HU on CT. The results from dimensional comparison analysis of the printed phantoms with the digital test phantoms using non-contact profile measurement showed a mean accuracy of 99.07 % and that of micro-CT volumetric analysis showed mean volumetric accuracy of 84.80–94.91%. The material and printing costs of developing 24 test phantoms was 83.00 Euro. Conclusions: The study shows that additive manufacturing-guided macrostructure manipulation modifies successfully the radiographic visibility of a material in CBCT imaging with 1 mm3 resolution, helping customization of imaging phantoms.http://www.sciencedirect.com/science/article/pii/S0939388922000630CTCone Beam CTMicro-CTAdditive manufacturingProfilometerImaging phantoms |
| spellingShingle | Sepideh Hatamikia Gunpreet Oberoi Anna Zacher Gernot Kronreif Wolfgang Birkfellner Joachim Kettenbach Stefanie Ponti Andrea Lorenz Martin Buschmann Laszlo Jaksa Nikolaus Irnstorfer Ewald Unger Additively manufactured test phantoms for mimicking soft tissue radiation attenuation in CBCT using Polyjet technology Zeitschrift für Medizinische Physik CT Cone Beam CT Micro-CT Additive manufacturing Profilometer Imaging phantoms |
| title | Additively manufactured test phantoms for mimicking soft tissue radiation attenuation in CBCT using Polyjet technology |
| title_full | Additively manufactured test phantoms for mimicking soft tissue radiation attenuation in CBCT using Polyjet technology |
| title_fullStr | Additively manufactured test phantoms for mimicking soft tissue radiation attenuation in CBCT using Polyjet technology |
| title_full_unstemmed | Additively manufactured test phantoms for mimicking soft tissue radiation attenuation in CBCT using Polyjet technology |
| title_short | Additively manufactured test phantoms for mimicking soft tissue radiation attenuation in CBCT using Polyjet technology |
| title_sort | additively manufactured test phantoms for mimicking soft tissue radiation attenuation in cbct using polyjet technology |
| topic | CT Cone Beam CT Micro-CT Additive manufacturing Profilometer Imaging phantoms |
| url | http://www.sciencedirect.com/science/article/pii/S0939388922000630 |
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