Quantum Dots for Cancer Research: Current Status, Remaining Issues, and Future Perspectives

Cancer is a major threat to public health in the 21st century because it is one of the leading causes of death worldwide. The mechanisms of carcinogenesis, cancer invasion, and metastasis remain unclear. Thus, the development of a novel approach for cancer detection is urgent, and real-time monitori...

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Main Authors: Min Fang, Chun-wei Peng, Dai-Wen Pang, Yan Li
Format: Article
Language:English
Published: China Anti-Cancer Association 2012-09-01
Series:Cancer Biology & Medicine
Subjects:
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/118
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author Min Fang
Chun-wei Peng
Dai-Wen Pang
Yan Li
author_facet Min Fang
Chun-wei Peng
Dai-Wen Pang
Yan Li
author_sort Min Fang
collection DOAJ
description Cancer is a major threat to public health in the 21st century because it is one of the leading causes of death worldwide. The mechanisms of carcinogenesis, cancer invasion, and metastasis remain unclear. Thus, the development of a novel approach for cancer detection is urgent, and real-time monitoring is crucial in revealing its underlying biological mechanisms. With the optical and chemical advantages of quantum dots (QDs), QD-based nanotechnology is helpful in constructing a biomedical imaging platform for cancer behavior study. This review mainly focuses on the application of QD-based nanotechnology in cancer cell imaging and tumor microenvironment studies both <i>in vivo</i> and <i>in vitro</i>, as well as the remaining issues and future perspectives.
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spelling doaj.art-0334eb2665bb41a89a9e4c38ec2a63b72022-12-22T02:57:35ZengChina Anti-Cancer AssociationCancer Biology & Medicine2095-39412095-39412012-09-019315116310.3969/j.issn.2095-3941.2012.03.0012012030001Quantum Dots for Cancer Research: Current Status, Remaining Issues, and Future PerspectivesMin Fang0Chun-wei Peng1Dai-Wen Pang2Yan Li3Department of Oncology, Zhongnan Hospital of Wuhan University, Hubei Key Laboratory of Tumor Biological Behaviors & Hubei Cancer Clinical Study Center, Wuhan 430071, China;Department of Oncology, Zhongnan Hospital of Wuhan University, Hubei Key Laboratory of Tumor Biological Behaviors & Hubei Cancer Clinical Study Center, Wuhan 430071, China;Key Laboratory of Analytical Chemistry for Biology and Medicine(Ministry of Education), College of Chemistry and Molecular Sciences, and State Key Laboratory of Virology, Wuhan University, Wuhan 430072, ChinaDepartment of Oncology, Zhongnan Hospital of Wuhan University, Hubei Key Laboratory of Tumor Biological Behaviors & Hubei Cancer Clinical Study Center, Wuhan 430071, China;Cancer is a major threat to public health in the 21st century because it is one of the leading causes of death worldwide. The mechanisms of carcinogenesis, cancer invasion, and metastasis remain unclear. Thus, the development of a novel approach for cancer detection is urgent, and real-time monitoring is crucial in revealing its underlying biological mechanisms. With the optical and chemical advantages of quantum dots (QDs), QD-based nanotechnology is helpful in constructing a biomedical imaging platform for cancer behavior study. This review mainly focuses on the application of QD-based nanotechnology in cancer cell imaging and tumor microenvironment studies both <i>in vivo</i> and <i>in vitro</i>, as well as the remaining issues and future perspectives.http://www.cancerbiomed.org/index.php/cocr/article/view/118quantum dotsmolecular imagingmultimodality probes
spellingShingle Min Fang
Chun-wei Peng
Dai-Wen Pang
Yan Li
Quantum Dots for Cancer Research: Current Status, Remaining Issues, and Future Perspectives
Cancer Biology & Medicine
quantum dots
molecular imaging
multimodality probes
title Quantum Dots for Cancer Research: Current Status, Remaining Issues, and Future Perspectives
title_full Quantum Dots for Cancer Research: Current Status, Remaining Issues, and Future Perspectives
title_fullStr Quantum Dots for Cancer Research: Current Status, Remaining Issues, and Future Perspectives
title_full_unstemmed Quantum Dots for Cancer Research: Current Status, Remaining Issues, and Future Perspectives
title_short Quantum Dots for Cancer Research: Current Status, Remaining Issues, and Future Perspectives
title_sort quantum dots for cancer research current status remaining issues and future perspectives
topic quantum dots
molecular imaging
multimodality probes
url http://www.cancerbiomed.org/index.php/cocr/article/view/118
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AT chunweipeng quantumdotsforcancerresearchcurrentstatusremainingissuesandfutureperspectives
AT daiwenpang quantumdotsforcancerresearchcurrentstatusremainingissuesandfutureperspectives
AT yanli quantumdotsforcancerresearchcurrentstatusremainingissuesandfutureperspectives