Receptor-Binding Domain Proteins of SARS-CoV-2 Variants Elicited Robust Antibody Responses Cross-Reacting with Wild-Type and Mutant Viruses in Mice

Receptor-Binding Domain Proteins of SARS-CoV-2 Variants Elicited Robust Antibody Responses Cross-Reacting with Wild-Type and Mutant Viruses in Mice

Multiple variants of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) have spread around the world, but the neutralizing effects of antibodies induced by the existing vaccines have declined, which highlights the importance of developing vaccines against mutant virus strains. In this stud...

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Bibliographic Details
Main Authors: Juan Shi, Xiaoxiao Jin, Yan Ding, Xiaotao Liu, Anran Shen, Yandan Wu, Min Peng, Chuanlai Shen
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Vaccines
Subjects:
SARS-CoV-2
variants
spike protein
receptor-binding domain
immunogenicity
neutralizing antibodies
Online Access:https://www.mdpi.com/2076-393X/9/12/1383

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