Low expression of lysosome-related genes KCNE1, NPC2, and SFTPD promote cancer cell proliferation and tumor associated M2 macrophage polarization in lung adenocarcinoma

Low expression of lysosome-related genes KCNE1, NPC2, and SFTPD promote cancer cell proliferation and tumor associated M2 macrophage polarization in lung adenocarcinoma

Background: Recent research has shown that lysosomes play a critical role in the onset and progression of malignancy by regulating tumor cell death through several mechanisms. Nevertheless, the involvement of lysosome-associated genes (LSAGs) in lung adenocarcinoma (LUAD) is still not well understoo...

Full description

Bibliographic Details
Main Authors: Zi-Ming Wang, Zhi-Lin Ning, Chao Ma, Tang-Bin Liu, Bo Tao, Liang Guo
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Heliyon
Subjects:
Lung cancer
Lysosome
Prognosis
Immunotherapy
Macrophage
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024036065

Internet

http://www.sciencedirect.com/science/article/pii/S2405844024036065

Similar Items