Design and fabrication of a realistic anthropomorphic heterogeneous head phantom for MR purposes.

The purpose of this study is to design an anthropomorphic heterogeneous head phantom that can be used for MRI and other electromagnetic applications.An eight compartment, physical anthropomorphic head phantom was developed from a 3T MRI dataset of a healthy male. The designed phantom was successfull...

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Main Authors: Sossena Wood, Narayanan Krishnamurthy, Tales Santini, Shailesh B Raval, Nadim Farhat, John Andy Holmes, Tamer S Ibrahim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5555696?pdf=render
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author Sossena Wood
Narayanan Krishnamurthy
Tales Santini
Shailesh B Raval
Nadim Farhat
John Andy Holmes
Tamer S Ibrahim
author_facet Sossena Wood
Narayanan Krishnamurthy
Tales Santini
Shailesh B Raval
Nadim Farhat
John Andy Holmes
Tamer S Ibrahim
author_sort Sossena Wood
collection DOAJ
description The purpose of this study is to design an anthropomorphic heterogeneous head phantom that can be used for MRI and other electromagnetic applications.An eight compartment, physical anthropomorphic head phantom was developed from a 3T MRI dataset of a healthy male. The designed phantom was successfully built and preliminarily evaluated through an application that involves electromagnetic-tissue interactions: MRI (due to it being an available resource). The developed phantom was filled with media possessing electromagnetic constitutive parameters that correspond to biological tissues at ~297 MHz. A preliminary comparison between an in-vivo human volunteer (based on whom the anthropomorphic head phantom was created) and various phantoms types, one being the anthropomorphic heterogeneous head phantom, were performed using a 7 Tesla human MRI scanner.Echo planar imaging was performed and minimal ghosting and fluctuations were observed using the proposed anthropomorphic phantom. The magnetic field distributions (during MRI experiments at 7 Tesla) and the scattering parameter (measured using a network analyzer) were most comparable between the anthropomorphic heterogeneous head phantom and an in-vivo human volunteer.The developed anthropomorphic heterogeneous head phantom can be used as a resource to various researchers in applications that involve electromagnetic-biological tissue interactions such as MRI.
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spelling doaj.art-0336c44481584ecabbff697fcd1ba6912022-12-22T03:58:15ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01128e018316810.1371/journal.pone.0183168Design and fabrication of a realistic anthropomorphic heterogeneous head phantom for MR purposes.Sossena WoodNarayanan KrishnamurthyTales SantiniShailesh B RavalNadim FarhatJohn Andy HolmesTamer S IbrahimThe purpose of this study is to design an anthropomorphic heterogeneous head phantom that can be used for MRI and other electromagnetic applications.An eight compartment, physical anthropomorphic head phantom was developed from a 3T MRI dataset of a healthy male. The designed phantom was successfully built and preliminarily evaluated through an application that involves electromagnetic-tissue interactions: MRI (due to it being an available resource). The developed phantom was filled with media possessing electromagnetic constitutive parameters that correspond to biological tissues at ~297 MHz. A preliminary comparison between an in-vivo human volunteer (based on whom the anthropomorphic head phantom was created) and various phantoms types, one being the anthropomorphic heterogeneous head phantom, were performed using a 7 Tesla human MRI scanner.Echo planar imaging was performed and minimal ghosting and fluctuations were observed using the proposed anthropomorphic phantom. The magnetic field distributions (during MRI experiments at 7 Tesla) and the scattering parameter (measured using a network analyzer) were most comparable between the anthropomorphic heterogeneous head phantom and an in-vivo human volunteer.The developed anthropomorphic heterogeneous head phantom can be used as a resource to various researchers in applications that involve electromagnetic-biological tissue interactions such as MRI.http://europepmc.org/articles/PMC5555696?pdf=render
spellingShingle Sossena Wood
Narayanan Krishnamurthy
Tales Santini
Shailesh B Raval
Nadim Farhat
John Andy Holmes
Tamer S Ibrahim
Design and fabrication of a realistic anthropomorphic heterogeneous head phantom for MR purposes.
PLoS ONE
title Design and fabrication of a realistic anthropomorphic heterogeneous head phantom for MR purposes.
title_full Design and fabrication of a realistic anthropomorphic heterogeneous head phantom for MR purposes.
title_fullStr Design and fabrication of a realistic anthropomorphic heterogeneous head phantom for MR purposes.
title_full_unstemmed Design and fabrication of a realistic anthropomorphic heterogeneous head phantom for MR purposes.
title_short Design and fabrication of a realistic anthropomorphic heterogeneous head phantom for MR purposes.
title_sort design and fabrication of a realistic anthropomorphic heterogeneous head phantom for mr purposes
url http://europepmc.org/articles/PMC5555696?pdf=render
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