C-terminal mini-PEGylation of a marine peptide N6 had potent antibacterial and anti-inflammatory properties against Escherichia coli and Salmonella strains in vitro and in vivo

C-terminal mini-PEGylation of a marine peptide N6 had potent antibacterial and anti-inflammatory properties against Escherichia coli and Salmonella strains in vitro and in vivo

Abstract Background Enteropathogenic Escherichia coli and Salmonella pullorum are two important groups of zoonotic pathogens. At present, the treatment of intestinal pathogenic bacteria infection mainly relies on antibiotics, which directly inhibit or kill the pathogenic bacteria. However, due to lo...

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Bibliographic Details
Main Authors: Ting Li, Na Yang, Da Teng, Ruoyu Mao, Ya Hao, Xiumin Wang, Jianhua Wang
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Microbiology
Subjects:
Marine peptide-N6
PEGylation
Antibacterial activity
Anti-inflammatory activity
Intracorporeal distribution
Online Access:https://doi.org/10.1186/s12866-022-02534-w

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