Factors influencing quality of life and well being in metastatic prostate cancer patients

Introduction Improving health-related quality of life (HRQL) is the main goal of palliative care. It requires consensual management strategies and specific measures targeting modifiable factors that could affect the quality of life. Objectives The aim of this study was to identify factors influenci...

Full description

Bibliographic Details
Main Authors: K. Bouassida, A. Loghmari, M. Ben Othmen, G. Tlili, E. Acacha, W. Ben Abdallah, M. Kahloul, W. Hmida, M. Jaidane
Format: Article
Language:English
Published: Cambridge University Press 2023-03-01
Series:European Psychiatry
Online Access:https://www.cambridge.org/core/product/identifier/S0924933823019995/type/journal_article
_version_ 1797616687453831168
author K. Bouassida
A. Loghmari
M. Ben Othmen
G. Tlili
E. Acacha
W. Ben Abdallah
M. Kahloul
W. Hmida
M. Jaidane
author_facet K. Bouassida
A. Loghmari
M. Ben Othmen
G. Tlili
E. Acacha
W. Ben Abdallah
M. Kahloul
W. Hmida
M. Jaidane
author_sort K. Bouassida
collection DOAJ
description Introduction Improving health-related quality of life (HRQL) is the main goal of palliative care. It requires consensual management strategies and specific measures targeting modifiable factors that could affect the quality of life. Objectives The aim of this study was to identify factors influencing the quality of life of patients with metastatic prostate cancer in a limited resources country. Methods This is a retrospective and analytical study enrolling all patients with metastatic prostate cancer who were managed at medical oncology and urology consultations of two Tunisian teaching hospital. HRQL was measured using UCLA prostate cancer index and SF-36 SCALE. The influence of demographic and medical characteristics on HRQL was determined using t tests and analysis of variance, with Tukey’s correction for multiple comparisons. Multivariate linear regression was used to determine independent predictor Results This study enrolled 244 patients. The mean age was 72 years. The strongest determinants of overall HRQL after univariate analysis were: increased age (p = 0.006), lower income (p = 0.009), sexual function problems (p = 0.004), urinary function problems (p = 0.002) and symptoms such as pain (p = 0.001) and asthenia (p = 0.001). Conclusions Age, income, sexual and urinary functions are important determinants of HRQL in patients with metastatic prostate cancer that may require specific interventions. Disclosure of Interest None Declared
first_indexed 2024-03-11T07:44:50Z
format Article
id doaj.art-0338b9c830824973887daf003c80c06c
institution Directory Open Access Journal
issn 0924-9338
1778-3585
language English
last_indexed 2024-03-11T07:44:50Z
publishDate 2023-03-01
publisher Cambridge University Press
record_format Article
series European Psychiatry
spelling doaj.art-0338b9c830824973887daf003c80c06c2023-11-17T05:07:43ZengCambridge University PressEuropean Psychiatry0924-93381778-35852023-03-0166S943S94410.1192/j.eurpsy.2023.1999Factors influencing quality of life and well being in metastatic prostate cancer patientsK. Bouassida0A. Loghmari1M. Ben Othmen2G. Tlili3E. Acacha4W. Ben Abdallah5M. Kahloul6W. Hmida7M. Jaidane8UrologyUrologyUrologyUrologyUrologyUrologyAnesthesiology department, Sahloul teachin Hospital Sousse, Sousse, TunisiaUrologyUrology Introduction Improving health-related quality of life (HRQL) is the main goal of palliative care. It requires consensual management strategies and specific measures targeting modifiable factors that could affect the quality of life. Objectives The aim of this study was to identify factors influencing the quality of life of patients with metastatic prostate cancer in a limited resources country. Methods This is a retrospective and analytical study enrolling all patients with metastatic prostate cancer who were managed at medical oncology and urology consultations of two Tunisian teaching hospital. HRQL was measured using UCLA prostate cancer index and SF-36 SCALE. The influence of demographic and medical characteristics on HRQL was determined using t tests and analysis of variance, with Tukey’s correction for multiple comparisons. Multivariate linear regression was used to determine independent predictor Results This study enrolled 244 patients. The mean age was 72 years. The strongest determinants of overall HRQL after univariate analysis were: increased age (p = 0.006), lower income (p = 0.009), sexual function problems (p = 0.004), urinary function problems (p = 0.002) and symptoms such as pain (p = 0.001) and asthenia (p = 0.001). Conclusions Age, income, sexual and urinary functions are important determinants of HRQL in patients with metastatic prostate cancer that may require specific interventions. Disclosure of Interest None Declaredhttps://www.cambridge.org/core/product/identifier/S0924933823019995/type/journal_article
spellingShingle K. Bouassida
A. Loghmari
M. Ben Othmen
G. Tlili
E. Acacha
W. Ben Abdallah
M. Kahloul
W. Hmida
M. Jaidane
Factors influencing quality of life and well being in metastatic prostate cancer patients
European Psychiatry
title Factors influencing quality of life and well being in metastatic prostate cancer patients
title_full Factors influencing quality of life and well being in metastatic prostate cancer patients
title_fullStr Factors influencing quality of life and well being in metastatic prostate cancer patients
title_full_unstemmed Factors influencing quality of life and well being in metastatic prostate cancer patients
title_short Factors influencing quality of life and well being in metastatic prostate cancer patients
title_sort factors influencing quality of life and well being in metastatic prostate cancer patients
url https://www.cambridge.org/core/product/identifier/S0924933823019995/type/journal_article
work_keys_str_mv AT kbouassida factorsinfluencingqualityoflifeandwellbeinginmetastaticprostatecancerpatients
AT aloghmari factorsinfluencingqualityoflifeandwellbeinginmetastaticprostatecancerpatients
AT mbenothmen factorsinfluencingqualityoflifeandwellbeinginmetastaticprostatecancerpatients
AT gtlili factorsinfluencingqualityoflifeandwellbeinginmetastaticprostatecancerpatients
AT eacacha factorsinfluencingqualityoflifeandwellbeinginmetastaticprostatecancerpatients
AT wbenabdallah factorsinfluencingqualityoflifeandwellbeinginmetastaticprostatecancerpatients
AT mkahloul factorsinfluencingqualityoflifeandwellbeinginmetastaticprostatecancerpatients
AT whmida factorsinfluencingqualityoflifeandwellbeinginmetastaticprostatecancerpatients
AT mjaidane factorsinfluencingqualityoflifeandwellbeinginmetastaticprostatecancerpatients