Appropriateness of Mini-Invasive Approaches for Nausea and Vomiting Refractory to Medical Therapy in Palliative Care Setting: A Case Report
Introduction: Nausea and vomiting are frequent multifactorial symptoms in oncological patients. These manifestations, mainly affecting the advanced disease stages, may lead to existential, psychological, and physical suffering, with a negative impact on the quality of life (QoL) of the individual an...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2024-02-01
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| Series: | Case Reports in Oncology |
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| Online Access: | https://beta.karger.com/Article/FullText/536218 |
| _version_ | 1797262551911759872 |
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| author | Chiara Casadio Elisa Tassinari Riccardo Carloni Romina Rossi Maria Valentina Tenti Laura Fabbri Marco Maltoni |
| author_facet | Chiara Casadio Elisa Tassinari Riccardo Carloni Romina Rossi Maria Valentina Tenti Laura Fabbri Marco Maltoni |
| author_sort | Chiara Casadio |
| collection | DOAJ |
| description | Introduction: Nausea and vomiting are frequent multifactorial symptoms in oncological patients. These manifestations, mainly affecting the advanced disease stages, may lead to existential, psychological, and physical suffering, with a negative impact on the quality of life (QoL) of the individual and his family. The medical approach makes use of a wide range of drugs, with different antiemetic potency and various mechanisms of action, taking into account the etiology and the patient’s response to the different therapeutic strategies. In recent years, in addition to pharmacological treatments, some endoscopic procedures have been integrated into clinical practice as promising palliative approaches. Case Presentation: Herein, we describe and discuss a case of a 64-year-old female affected by advanced stage pancreatic adenocarcinoma, in which different techniques – both medical and endoscopic – have been used to approach a refractory symptomatology with a negative impact on the patient’s QoL. In the context of a multidisciplinary approach in primary palliative care, a tailored intervention encompassing invasive methods for palliative purposes, may be considered adequate and appropriate when the prognostic expectation and the physical functionality indices allow it. Conclusion: Minimally invasive palliative interventions should be offered to patients with advanced cancer when symptoms become refractory to standard medical therapies, as part of the holistic approach in modern treatments. Therefore, the integration of an early palliative approach into the patient’s therapeutic path becomes essential for the management of all the individual’s needs. |
| first_indexed | 2024-03-07T19:39:14Z |
| format | Article |
| id | doaj.art-033957925eeb43f9adfafc571e8940a9 |
| institution | Directory Open Access Journal |
| issn | 1662-6575 |
| language | English |
| last_indexed | 2024-04-24T23:58:55Z |
| publishDate | 2024-02-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Oncology |
| spelling | doaj.art-033957925eeb43f9adfafc571e8940a92024-03-14T08:00:37ZengKarger PublishersCase Reports in Oncology1662-65752024-02-0117127027610.1159/000536218536218Appropriateness of Mini-Invasive Approaches for Nausea and Vomiting Refractory to Medical Therapy in Palliative Care Setting: A Case ReportChiara Casadio0Elisa Tassinari1Riccardo Carloni2Romina Rossi3Maria Valentina Tenti4Laura Fabbri5Marco Maltoni6Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalyMedical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalyMedical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalyIRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) “Dino Amadori”, Meldola, ItalyPalliative Care Unit, Azienda Unità Sanitaria Locale (AUSL) Romagna, Forli, ItalyPalliative Care Unit, Azienda Unità Sanitaria Locale (AUSL) Romagna, Forli, ItalyPalliative Care Unit, Azienda Unità Sanitaria Locale (AUSL) Romagna, Forli, ItalyIntroduction: Nausea and vomiting are frequent multifactorial symptoms in oncological patients. These manifestations, mainly affecting the advanced disease stages, may lead to existential, psychological, and physical suffering, with a negative impact on the quality of life (QoL) of the individual and his family. The medical approach makes use of a wide range of drugs, with different antiemetic potency and various mechanisms of action, taking into account the etiology and the patient’s response to the different therapeutic strategies. In recent years, in addition to pharmacological treatments, some endoscopic procedures have been integrated into clinical practice as promising palliative approaches. Case Presentation: Herein, we describe and discuss a case of a 64-year-old female affected by advanced stage pancreatic adenocarcinoma, in which different techniques – both medical and endoscopic – have been used to approach a refractory symptomatology with a negative impact on the patient’s QoL. In the context of a multidisciplinary approach in primary palliative care, a tailored intervention encompassing invasive methods for palliative purposes, may be considered adequate and appropriate when the prognostic expectation and the physical functionality indices allow it. Conclusion: Minimally invasive palliative interventions should be offered to patients with advanced cancer when symptoms become refractory to standard medical therapies, as part of the holistic approach in modern treatments. Therefore, the integration of an early palliative approach into the patient’s therapeutic path becomes essential for the management of all the individual’s needs.https://beta.karger.com/Article/FullText/536218palliative carenauseavomitingendoscopic approachesgastrointestinal cancers |
| spellingShingle | Chiara Casadio Elisa Tassinari Riccardo Carloni Romina Rossi Maria Valentina Tenti Laura Fabbri Marco Maltoni Appropriateness of Mini-Invasive Approaches for Nausea and Vomiting Refractory to Medical Therapy in Palliative Care Setting: A Case Report Case Reports in Oncology palliative care nausea vomiting endoscopic approaches gastrointestinal cancers |
| title | Appropriateness of Mini-Invasive Approaches for Nausea and Vomiting Refractory to Medical Therapy in Palliative Care Setting: A Case Report |
| title_full | Appropriateness of Mini-Invasive Approaches for Nausea and Vomiting Refractory to Medical Therapy in Palliative Care Setting: A Case Report |
| title_fullStr | Appropriateness of Mini-Invasive Approaches for Nausea and Vomiting Refractory to Medical Therapy in Palliative Care Setting: A Case Report |
| title_full_unstemmed | Appropriateness of Mini-Invasive Approaches for Nausea and Vomiting Refractory to Medical Therapy in Palliative Care Setting: A Case Report |
| title_short | Appropriateness of Mini-Invasive Approaches for Nausea and Vomiting Refractory to Medical Therapy in Palliative Care Setting: A Case Report |
| title_sort | appropriateness of mini invasive approaches for nausea and vomiting refractory to medical therapy in palliative care setting a case report |
| topic | palliative care nausea vomiting endoscopic approaches gastrointestinal cancers |
| url | https://beta.karger.com/Article/FullText/536218 |
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