Intestinal and fecal pH in human health
Gut microbiota has been reported to be closely related to host energy metabolism and immunity, and thus influence the development and progression of various human diseases. To date, the gut microbial metabolites such as short-chain fatty acids, defensins, cathelicidins, and lactoferrin in feces have...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-07-01
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| Series: | Frontiers in Microbiomes |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/frmbi.2023.1192316/full |
| _version_ | 1797772077637304320 |
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| author | Ryodai Yamamura Kumi Y. Inoue Kumi Y. Inoue Kunihiko Nishino Kunihiko Nishino Kunihiko Nishino Seiji Yamasaki Seiji Yamasaki Seiji Yamasaki Seiji Yamasaki |
| author_facet | Ryodai Yamamura Kumi Y. Inoue Kumi Y. Inoue Kunihiko Nishino Kunihiko Nishino Kunihiko Nishino Seiji Yamasaki Seiji Yamasaki Seiji Yamasaki Seiji Yamasaki |
| author_sort | Ryodai Yamamura |
| collection | DOAJ |
| description | Gut microbiota has been reported to be closely related to host energy metabolism and immunity, and thus influence the development and progression of various human diseases. To date, the gut microbial metabolites such as short-chain fatty acids, defensins, cathelicidins, and lactoferrin in feces have been investigated as biomarkers associated with various disease conditions. In this review, we introduce intestinal and fecal pH, which is relatively easy and rapid to measure compared to the composition of the gut microbiota and its metabolites. In particular, this review presents the distribution of pH in the human body, its role and clinical significance, and various factors that affect intestinal and fecal pH, including the gut microbiota and its metabolites. |
| first_indexed | 2024-03-12T21:45:53Z |
| format | Article |
| id | doaj.art-033fbc7b3e8d4dc0a1c2d512f91545fe |
| institution | Directory Open Access Journal |
| issn | 2813-4338 |
| language | English |
| last_indexed | 2024-03-12T21:45:53Z |
| publishDate | 2023-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiomes |
| spelling | doaj.art-033fbc7b3e8d4dc0a1c2d512f91545fe2023-07-26T11:02:58ZengFrontiers Media S.A.Frontiers in Microbiomes2813-43382023-07-01210.3389/frmbi.2023.11923161192316Intestinal and fecal pH in human healthRyodai Yamamura0Kumi Y. Inoue1Kumi Y. Inoue2Kunihiko Nishino3Kunihiko Nishino4Kunihiko Nishino5Seiji Yamasaki6Seiji Yamasaki7Seiji Yamasaki8Seiji Yamasaki9Institute for Genetic Medicine, Hokkaido University, Sapporo, JapanGraduate Faculty of Interdisciplinary Research, University of Yamanashi, Kofu, JapanGraduate School of Environmental Studies, Tohoku University, Sendai, JapanSANKEN (The Institute of Scientific and Industrial Research), Osaka University, Ibaraki, JapanGraduate School of Pharmaceutical Sciences, Osaka University, Suita, JapanCenter for Infectious Disease Education and Research, Osaka University, Suita, JapanSANKEN (The Institute of Scientific and Industrial Research), Osaka University, Ibaraki, JapanGraduate School of Pharmaceutical Sciences, Osaka University, Suita, JapanCenter for Infectious Disease Education and Research, Osaka University, Suita, JapanInstitute for Advanced Co-Creation Studies, Osaka University, Suita, JapanGut microbiota has been reported to be closely related to host energy metabolism and immunity, and thus influence the development and progression of various human diseases. To date, the gut microbial metabolites such as short-chain fatty acids, defensins, cathelicidins, and lactoferrin in feces have been investigated as biomarkers associated with various disease conditions. In this review, we introduce intestinal and fecal pH, which is relatively easy and rapid to measure compared to the composition of the gut microbiota and its metabolites. In particular, this review presents the distribution of pH in the human body, its role and clinical significance, and various factors that affect intestinal and fecal pH, including the gut microbiota and its metabolites.https://www.frontiersin.org/articles/10.3389/frmbi.2023.1192316/fullgut microbiotafecal pHbiomarkersshort-chain fatty acidsmetabolitesmetabolism |
| spellingShingle | Ryodai Yamamura Kumi Y. Inoue Kumi Y. Inoue Kunihiko Nishino Kunihiko Nishino Kunihiko Nishino Seiji Yamasaki Seiji Yamasaki Seiji Yamasaki Seiji Yamasaki Intestinal and fecal pH in human health Frontiers in Microbiomes gut microbiota fecal pH biomarkers short-chain fatty acids metabolites metabolism |
| title | Intestinal and fecal pH in human health |
| title_full | Intestinal and fecal pH in human health |
| title_fullStr | Intestinal and fecal pH in human health |
| title_full_unstemmed | Intestinal and fecal pH in human health |
| title_short | Intestinal and fecal pH in human health |
| title_sort | intestinal and fecal ph in human health |
| topic | gut microbiota fecal pH biomarkers short-chain fatty acids metabolites metabolism |
| url | https://www.frontiersin.org/articles/10.3389/frmbi.2023.1192316/full |
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