Comparing 2 crystal structures and 12 AlphaFold2-predicted human membrane glucose transporters and their water-soluble glutamine, threonine and tyrosine variants

Membrane transporters including glucose transporters (GLUTs) are involved in cellular energy supplies, cell metabolism and other vital biological activities. They have also been implicated in cancer proliferation and metastasis, thus they represent an important target in combatting cancer. However,...

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Bibliographic Details
Main Authors: Eva Smorodina, Fei Tao, Rui Qing, David Jin, Steve Yang, Shuguang Zhang
Format: Article
Language:English
Published: Cambridge University Press 2022-01-01
Series:QRB Discovery
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S2633289222000060/type/journal_article