Uniparental genetic markers in South Amerindians
A comprehensive review of uniparental systems in South Amerindians was undertaken. Variability in the Y-chromosome haplogroups were assessed in 68 populations and 1,814 individuals whereas that of Y-STR markers was assessed in 29 populations and 590 subjects. Variability in the mitochondrial DNA (mt...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Genética
2012-01-01
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| Series: | Genetics and Molecular Biology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000300001 |
| _version_ | 1819289525047787520 |
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| author | Rafael Bisso-Machado Maria Cátira Bortolini Francisco Mauro Salzano |
| author_facet | Rafael Bisso-Machado Maria Cátira Bortolini Francisco Mauro Salzano |
| author_sort | Rafael Bisso-Machado |
| collection | DOAJ |
| description | A comprehensive review of uniparental systems in South Amerindians was undertaken. Variability in the Y-chromosome haplogroups were assessed in 68 populations and 1,814 individuals whereas that of Y-STR markers was assessed in 29 populations and 590 subjects. Variability in the mitochondrial DNA (mtDNA) haplogroup was examined in 108 populations and 6,697 persons, and sequencing studies used either the complete mtDNA genome or the highly variable segments 1 and 2. The diversity of the markers made it difficult to establish a general picture of Y-chromosome variability in the populations studied. However, haplogroup Q1a3a* was almost always the most prevalent whereas Q1a3* occurred equally in all regions, which suggested its prevalence among the early colonizers. The STR allele frequencies were used to derive a possible ancient Native American Q-clade chromosome haplotype and five of six STR loci showed significant geographic variation. Geographic and linguistic factors moderately influenced the mtDNA distributions (6% and 7%, respectively) and mtDNA haplogroups A and D correlated positively and negatively, respectively, with latitude. The data analyzed here provide rich material for understanding the biological history of South Amerindians and can serve as a basis for comparative studies involving other types of data, such as cultural data. |
| first_indexed | 2024-12-24T03:08:14Z |
| format | Article |
| id | doaj.art-0340c4f89c7e4533a141844271d744bc |
| institution | Directory Open Access Journal |
| issn | 1415-4757 1678-4685 |
| language | English |
| last_indexed | 2024-12-24T03:08:14Z |
| publishDate | 2012-01-01 |
| publisher | Sociedade Brasileira de Genética |
| record_format | Article |
| series | Genetics and Molecular Biology |
| spelling | doaj.art-0340c4f89c7e4533a141844271d744bc2022-12-21T17:17:55ZengSociedade Brasileira de GenéticaGenetics and Molecular Biology1415-47571678-46852012-01-01352365387Uniparental genetic markers in South AmerindiansRafael Bisso-MachadoMaria Cátira BortoliniFrancisco Mauro SalzanoA comprehensive review of uniparental systems in South Amerindians was undertaken. Variability in the Y-chromosome haplogroups were assessed in 68 populations and 1,814 individuals whereas that of Y-STR markers was assessed in 29 populations and 590 subjects. Variability in the mitochondrial DNA (mtDNA) haplogroup was examined in 108 populations and 6,697 persons, and sequencing studies used either the complete mtDNA genome or the highly variable segments 1 and 2. The diversity of the markers made it difficult to establish a general picture of Y-chromosome variability in the populations studied. However, haplogroup Q1a3a* was almost always the most prevalent whereas Q1a3* occurred equally in all regions, which suggested its prevalence among the early colonizers. The STR allele frequencies were used to derive a possible ancient Native American Q-clade chromosome haplotype and five of six STR loci showed significant geographic variation. Geographic and linguistic factors moderately influenced the mtDNA distributions (6% and 7%, respectively) and mtDNA haplogroups A and D correlated positively and negatively, respectively, with latitude. The data analyzed here provide rich material for understanding the biological history of South Amerindians and can serve as a basis for comparative studies involving other types of data, such as cultural data.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000300001geneticslanguage and geographymitochondrial DNANative AmericansSouth AmerindiansY-chromosome |
| spellingShingle | Rafael Bisso-Machado Maria Cátira Bortolini Francisco Mauro Salzano Uniparental genetic markers in South Amerindians Genetics and Molecular Biology genetics language and geography mitochondrial DNA Native Americans South Amerindians Y-chromosome |
| title | Uniparental genetic markers in South Amerindians |
| title_full | Uniparental genetic markers in South Amerindians |
| title_fullStr | Uniparental genetic markers in South Amerindians |
| title_full_unstemmed | Uniparental genetic markers in South Amerindians |
| title_short | Uniparental genetic markers in South Amerindians |
| title_sort | uniparental genetic markers in south amerindians |
| topic | genetics language and geography mitochondrial DNA Native Americans South Amerindians Y-chromosome |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000300001 |
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