Comparative evaluation of functional constipation prevention methods in pregnant women
Aim. To perform a comparative evaluation of different methods for preventing functional constipation in pregnant women. Materials and methods. The study included 150 pregnant women aged 18 to 42 years, 22 to 36 weeks of gestation, with functional constipation. Group 1 included 50 patients who rec...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
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IP Berlin A.V.
2022-11-01
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| Series: | Гинекология |
| Subjects: | |
| Online Access: | https://gynecology.orscience.ru/2079-5831/article/viewFile/115000/89773 |
| _version_ | 1797985389679476736 |
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| author | Tatiana N. Rybakova Lyudmila V. Nazarova Maxim S. Kovalenko Igor I. Tuzlukov |
| author_facet | Tatiana N. Rybakova Lyudmila V. Nazarova Maxim S. Kovalenko Igor I. Tuzlukov |
| author_sort | Tatiana N. Rybakova |
| collection | DOAJ |
| description | Aim. To perform a comparative evaluation of different methods for preventing functional constipation in pregnant women.
Materials and methods. The study included 150 pregnant women aged 18 to 42 years, 22 to 36 weeks of gestation, with functional constipation. Group 1 included 50 patients who received dietary fiber OptiFibre in addition to diet therapy; group 2 included 50 patients who received diet therapy in combination with lactulose; group 3, the control group, included 50 pregnant women who received corrective diet therapy only. The outcomes were evaluated on day 14 of observation.
Results. A diet only was not sufficiently effective in normalizing stools in pregnant women with a gestational age of 2236 weeks. By day 14, stool frequency was restored in groups 1 and 2 patients. However, during lactulose use, gastrointestinal discomfort persisted more frequently; not all patients reported normal stools at the medium recommended dose, which required an increase of the dose. However, there were episodes of loose stool, which required discontinuation of the medicine. The best results were achieved with the combination of diet and partially hydrolyzed OptiFibre dietary fibers, both in terms of restoration of stool regularity, relief of associated gastrointestinal symptoms, and tolerance of the dietary fibers.
Conclusion. Soluble dietary fiber OptiFibre, combined with diet therapy, restores regular stools and resolves constipation in pregnant women. It is well tolerated and safe to use in obstetric practice. The findings suggest using OptiFibre for constipation in pregnant women. |
| first_indexed | 2024-04-11T07:16:13Z |
| format | Article |
| id | doaj.art-0341e55fe0b948f391b1efe24c66410a |
| institution | Directory Open Access Journal |
| issn | 2079-5696 2079-5831 |
| language | Russian |
| last_indexed | 2024-04-11T07:16:13Z |
| publishDate | 2022-11-01 |
| publisher | IP Berlin A.V. |
| record_format | Article |
| series | Гинекология |
| spelling | doaj.art-0341e55fe0b948f391b1efe24c66410a2022-12-22T04:37:54ZrusIP Berlin A.V.Гинекология2079-56962079-58312022-11-0124536937310.26442/20795696.2022.5.20192879460Comparative evaluation of functional constipation prevention methods in pregnant womenTatiana N. Rybakova0https://orcid.org/0000-0002-3868-3746Lyudmila V. Nazarova1https://orcid.org/0000-0001-5713-9829Maxim S. Kovalenko2https://orcid.org/0000-0002-2275-5426Igor I. Tuzlukov3https://orcid.org/0000-0002-6406-7226Pavlov Ryazan Medical UniversityPavlov Ryazan Medical UniversityPavlov Ryazan Medical UniversityPavlov Ryazan Medical UniversityAim. To perform a comparative evaluation of different methods for preventing functional constipation in pregnant women. Materials and methods. The study included 150 pregnant women aged 18 to 42 years, 22 to 36 weeks of gestation, with functional constipation. Group 1 included 50 patients who received dietary fiber OptiFibre in addition to diet therapy; group 2 included 50 patients who received diet therapy in combination with lactulose; group 3, the control group, included 50 pregnant women who received corrective diet therapy only. The outcomes were evaluated on day 14 of observation. Results. A diet only was not sufficiently effective in normalizing stools in pregnant women with a gestational age of 2236 weeks. By day 14, stool frequency was restored in groups 1 and 2 patients. However, during lactulose use, gastrointestinal discomfort persisted more frequently; not all patients reported normal stools at the medium recommended dose, which required an increase of the dose. However, there were episodes of loose stool, which required discontinuation of the medicine. The best results were achieved with the combination of diet and partially hydrolyzed OptiFibre dietary fibers, both in terms of restoration of stool regularity, relief of associated gastrointestinal symptoms, and tolerance of the dietary fibers. Conclusion. Soluble dietary fiber OptiFibre, combined with diet therapy, restores regular stools and resolves constipation in pregnant women. It is well tolerated and safe to use in obstetric practice. The findings suggest using OptiFibre for constipation in pregnant women.https://gynecology.orscience.ru/2079-5831/article/viewFile/115000/89773functional constipationstool disorderspregnancydietary fiberoptifibrelactulose |
| spellingShingle | Tatiana N. Rybakova Lyudmila V. Nazarova Maxim S. Kovalenko Igor I. Tuzlukov Comparative evaluation of functional constipation prevention methods in pregnant women Гинекология functional constipation stool disorders pregnancy dietary fiber optifibre lactulose |
| title | Comparative evaluation of functional constipation prevention methods in pregnant women |
| title_full | Comparative evaluation of functional constipation prevention methods in pregnant women |
| title_fullStr | Comparative evaluation of functional constipation prevention methods in pregnant women |
| title_full_unstemmed | Comparative evaluation of functional constipation prevention methods in pregnant women |
| title_short | Comparative evaluation of functional constipation prevention methods in pregnant women |
| title_sort | comparative evaluation of functional constipation prevention methods in pregnant women |
| topic | functional constipation stool disorders pregnancy dietary fiber optifibre lactulose |
| url | https://gynecology.orscience.ru/2079-5831/article/viewFile/115000/89773 |
| work_keys_str_mv | AT tatiananrybakova comparativeevaluationoffunctionalconstipationpreventionmethodsinpregnantwomen AT lyudmilavnazarova comparativeevaluationoffunctionalconstipationpreventionmethodsinpregnantwomen AT maximskovalenko comparativeevaluationoffunctionalconstipationpreventionmethodsinpregnantwomen AT igorituzlukov comparativeevaluationoffunctionalconstipationpreventionmethodsinpregnantwomen |