‘Off-the-Shelf’ Immunotherapy: Manufacture of CD8<sup>+</sup> T Cells Derived from Hematopoietic Stem Cells

‘Off-the-Shelf’ Immunotherapy: Manufacture of CD8<sup>+</sup> T Cells Derived from Hematopoietic Stem Cells

Cellular immunotherapy is revolutionizing cancer treatment. However, autologous transplants are complex, costly, and limited by the number and quality of T cells that can be isolated from and expanded for re-infusion into each patient. This paper demonstrates a stromal support cell-free in vitro met...

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Bibliographic Details
Main Authors: Nicholas Boyd, Kellie Cartledge, Huimin Cao, Vera Evtimov, Aleta Pupovac, Alan Trounson, Richard Boyd
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
HSC
CD8<sup>+</sup> T cells
differentiation
off-the-shelf immunotherapy
Online Access:https://www.mdpi.com/2073-4409/10/10/2631

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